Metals play vital roles in nutrients and medicines and provide chemical functionalities that
are not accessible to purely organic compounds. At least 10 metals are essential for human …

Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …

The Pt (IV) prodrug trans, trans, trans-[Pt (pyridine) 2 (N3) 2 (OH) 2](Pt1) and its coumarin
derivative trans, trans, trans-[Pt (pyridine) 2 (N3) 2 (OH)(coumarin-3-carboxylate)](Pt2) are …

High-resolution and rapid imaging of host cell ultrastructure can generate insights toward
viral disease mechanism, for example for a severe acute respiratory syndrome coronavirus …

Developing in silico models that accurately reflect a whole, functional cell is an ongoing
challenge in biology. Current efforts bring together mathematical models, probabilistic …

Abstract 3D correlative microscopy methods have revolutionized biomedical research,
allowing the acquisition of multidimensional information to gain an in-depth understanding …

Inter-organelle interactions are a vital part of normal cellular function; however, these have
proven difficult to quantify due to the range of scales encountered in cell biology and the …

X-ray tomography has become an indispensable tool for studying complex 3D interior
structures with high spatial resolution. Three-dimensional imaging using soft X-rays offers …

During host cell invasion, Shigella escapes to the cytosol and polymerizes actin for cell-to-
cell spread. To restrict cell-to-cell spread, host cells employ cell-autonomous immune …

Hydroxyapatite nanoparticles are popular tools in bone regeneration, but they have also
been used for gene delivery and as anticancer drugs. Understanding their mechanism of …