Background Despite the increasing knowledge of the etiology of neuropathic pain, this type
of chronic pain is resistant to available analgesics in approximately 50% of patients and …

Neuroinflammation is initiated with an aberrant innate immune response in the central
nervous system (CNS) and is involved in many neurological diseases. Inflammasomes are …

Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN) is a severe clinical problem and
potentially permanent side effect of cancer treatment. For the management of OIPN, accurate …

Chemotherapy-induced peripheral neuropathy is one of the most frequent dose-limiting side
effects, observed in patients receiving antineoplastic agents, persisting for up to two years …

Oxaliplatin (OHP)-induced peripheral neurotoxicity (OIPN), one of the major dose-limiting
side effects of colorectal cancer treatment, is characterized by both acute and chronic …

Severe burns develop a catecholamine surge, inducing severe damage to the organism,
raising the possibility of multisystem organ failure, and even death. The mechanisms of …

Chemotherapy-induced peripheral neuropathy (CIPN) is a prevalent, progressive and often
irreversible syndrome which causes chronic pain and poor quality of life in patients …