Evaluation of TNF-α, IL-10 and IL-6 cytokine production and their correlation with genotype variants amongst tuberculosis patients and their household contacts

L Joshi, M Ponnana, R Sivangala, LK Chelluri… - PloS one, 2015 - journals.plos.org
Background Household contacts of diagnostically established tuberculosis (TB) patients are
highly susceptible to disease development. It is surmised that cytokines perhaps play a …

Genetic polymorphisms of innate immunity-related inflammatory pathways and their association with factors related to type 2 diabetes

P Arora, B Garcia-Bailo, Z Dastani, D Brenner… - BMC Medical …, 2011 - Springer
Background Type 2 diabetes mellitus (T2DM) has been linked to a state of pre-clinical
chronic inflammation resulting from abnormalities in the innate immune pathway. Serum …

Immune-endocrine network in diabetes-tuberculosis nexus: does latent tuberculosis infection confer protection against meta-inflammation and insulin resistance?

V Aravindhan, S Yuvaraj - Frontiers in Endocrinology, 2024 - frontiersin.org
Tuberculosis patients with diabetes, have higher sputum bacillary load, delayed sputum
conversion, higher rates of drug resistance, higher lung cavitary involvement and extra …

[HTML][HTML] Associations between cytokine gene variations and severe persistent breast pain in women following breast cancer surgery

K Stephens, BA Cooper, C West, SM Paul… - The Journal of …, 2014 - Elsevier
Persistent pain following breast cancer surgery is a significant clinical problem. Although
immune mechanisms may play a role in the development and maintenance of persistent …

Polymorphisms in TICAM2 and IL1B are associated with TB

NB Hall, RP Igo, LL Malone, B Truitt, A Schnell… - Genes & …, 2015 - nature.com
Human genetic susceptibility for tuberculosis (TB) has been demonstrated by several
studies, but few have examined the multiple innate and adaptive immunity genes …

[HTML][HTML] IFN-gene polymorphisms as a risk factor for tuberculosis infection in Asian populations: A meta-analysis

BS Antony, C Nagarajan, KE Thomas… - The International …, 2023 - journals.lww.com
Background: The purpose of this meta-analysis is to verify that rs1861494 and rs2069718,
two polymorphisms in the IFN-gene, are associated with tuberculosis (TB) infection in Asian …

Coassociations between IL10 polymorphisms, IL-10 production, helminth infection, and asthma/wheeze in an urban tropical population in Brazil

CA Figueiredo, ML Barreto, NM Alcantara-Neves… - Journal of allergy and …, 2013 - Elsevier
BACKGROUND: Helminth infections are associated with protection against allergies. It is
postulated that IL-10 production after helminth infection suppresses skin hypersensitivity and …

Cytokine polymorphisms, their influence and levels in Brazilian patients with pulmonary tuberculosis during antituberculosis treatment

E Peresi, LRC Oliveira, WL da Silva… - Tuberculosis …, 2013 - Wiley Online Library
Cytokines play an essential role during active tuberculosis disease and cytokine genes have
been described in association with altered cytokine levels. Therefore, the aim of this study …

[PDF][PDF] Influence of interleukin-17 gene polymorphisms on the development of pulmonary tuberculosis

GC Shi, LG Zhang - Genet Mol Res, 2015 - funpecrp.com.br
We conducted a case-control study in a Chinese population to examine the correlations
between interleukin (IL)-17 gene polymorphisms and tuberculosis (TB) development. The …

Comparative genetic association analysis of human genetic susceptibility to pulmonary and lymph node tuberculosis

M Bose, A Giri, M Varma-Basil - Genes, 2023 - mdpi.com
Background: Tuberculosis (TB) manifests itself primarily in the lungs as pulmonary disease
(PTB) and sometimes disseminates to other organs to cause extra-pulmonary TB, such as …