Cholangiocarcinoma (CCA) encompasses diverse epithelial tumors historically associated
with poor outcomes due to an aggressive disease course, late diagnosis, and limited benefit …

Simple Summary The treatment of advanced and metastatic non-small cell lung cancer
(NSCLC) has changed dramatically in recent years due to advanced molecular diagnostics …

Tissue-based biopsy is the present main tool to explore the molecular landscape of cancer,
but it also has many limits to be frequently executed, being too invasive with the risk of side …

Simple Summary Non-small cell lung cancer (NSCLC) remains a significant cause of death
worldwide, despite the significant progresses to date. Multiple molecular alterations have …

Despite improved methods of diagnosis and the development of different treatments,
mortality from lung cancer remains surprisingly high. Non-small cell lung cancer (NSCLC) …

PURPOSE The aim of this study was to assess the cost-effectiveness of using next-
generation sequencing (NGS) versus single-gene testing (SgT) for the detection of genetic …

Simple Summary Mouth cancer often results in poor outcomes and requires the use of state-
of-the-art medical approaches to make its detection easy, individualized, and early. Liquid …

Simple Summary Anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer
(NSCLC) was first reported in 2007. Following the development of crizotinib as a tyrosine …

Simple Summary Lung cancer remains the first cause of cancer worldwide. The main reason
for this high rate of death from lung cancer is dissemination of the disease at the time of …

High-level MET amplification (METamp) is a primary driver in∼ 1%–2% of non-small cell
lung cancers (NSCLCs). Cohort B of the phase 2 VISION trial evaluates tepotinib, an oral …