A detailed overview of immune escape, antibody escape, partial vaccine escape of SARS-CoV-2 and their emerging variants with escape mutations
The infective SARS-CoV-2 is more prone to immune escape. Presently, the significant
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
variants of SARS-CoV-2 are emerging in due course of time with substantial mutations …
Cooperation of B cell lineages in induction of HIV-1-broadly neutralizing antibodies
Development of strategies for induction of HIV-1 broadly neutralizing antibodies (bnAbs) by
vaccines is a priority. Determining the steps of bnAb induction in HIV-1-infected individuals …
vaccines is a priority. Determining the steps of bnAb induction in HIV-1-infected individuals …
Relative resistance of HIV-1 founder viruses to control by interferon-alpha
AE Fenton-May, O Dibben, T Emmerich, H Ding… - Retrovirology, 2013 - Springer
Background Following mucosal human immunodeficiency virus type 1 (HIV-1) transmission,
type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa …
type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa …
Resistance to type 1 interferons is a major determinant of HIV-1 transmission fitness
SS Iyer, F Bibollet-Ruche… - Proceedings of the …, 2017 - National Acad Sciences
Sexual transmission of HIV-1 is an inefficient process, with only one or few variants of the
donor quasispecies establishing the new infection. A critical, and as yet unresolved …
donor quasispecies establishing the new infection. A critical, and as yet unresolved …
Interaction of the host and viral genome and their influence on HIV disease
RH Tough, PJ McLaren - Frontiers in Genetics, 2019 - frontiersin.org
The course of Human Immunodeficiency Virus type 1 (HIV) infection is a dynamic interplay in
which both host and viral genetic variation, among other factors, influence disease …
which both host and viral genetic variation, among other factors, influence disease …
The HIV-1 latent reservoir is largely sensitive to circulating T cells
HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral
variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus …
variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus …
Analysis of HLA A* 02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial
The RV144 HIV-1 vaccine trial demonstrated partial efficacy of 31% against HIV-1 infection.
Studies into possible correlates of protection found that antibodies specific to the V1 and V2 …
Studies into possible correlates of protection found that antibodies specific to the V1 and V2 …
The apparent interferon resistance of transmitted HIV-1 is possibly a consequence of enhanced replicative fitness
HIV-1 transmission via sexual exposure is an inefficient process. When transmission does
occur, newly infected individuals are colonized by the descendants of either a single virion …
occur, newly infected individuals are colonized by the descendants of either a single virion …
Quantification of Ebola virus replication kinetics in vitro
LE Liao, J Carruthers, SJ Smither… - PLoS computational …, 2020 - journals.plos.org
Mathematical modelling has successfully been used to provide quantitative descriptions of
many viral infections, but for the Ebola virus, which requires biosafety level 4 facilities for …
many viral infections, but for the Ebola virus, which requires biosafety level 4 facilities for …
Large-scale inference of correlation among mixed-type biological traits with phylogenetic multivariate probit models
Large-scale inference of correlation among mixed-type biological traits with phylogenetic
multivariate probit models Page 1 The Annals of Applied Statistics 2021, Vol. 15, No. 1, 230–251 …
multivariate probit models Page 1 The Annals of Applied Statistics 2021, Vol. 15, No. 1, 230–251 …