The increasing incidence of inflammatory bowel diseases (IBD) and the increasing severity
of the course of these diseases create the need for developing new methods of therapy. The …

The microbiome innovation has resulted in an umbrella term, postbiotics, which refers to non-
viable microbial cells, metabolic byproducts and their microbial components released after …

Objective Our goals were to evaluate the antitumour efficacy of Lactobacillus rhamnosus GG
(LGG) in combination with immune checkpoint blockade (ICB) immunotherapies on tumour …

Background Gut microbiota modulation has been demonstrated to be effective in protecting
patients against detrimental effects of anti-cancer therapies, as well as to improve the …

Intestinal mucositis, a cytotoxic side effect of the antineoplastic drug 5-fluorouracil (5-FU), is
characterized by ulceration, inflammation, diarrhea, and intense abdominal pain, making it …

The human gut microbiota has a significant effect on many aspects of human physiology
such as metabolism, nutrient absorption, and immune function. Imbalance of the microbiota …

Cancer is the second leading cause of elevated mortality worldwide. Thus, the development
of drugs and treatments is needed to enhance the survival rate of the cancer-affected …

Abstract The chemotherapeutic agent 5‐fluorouracil (5‐FU) causes intestinal mucositis with
severe diarrhoea, but the pathogenesis is not fully understood. In this study, we investigated …

Pathogens invade intestinal mucosal barrier through phagocytosis of antigen presenting
cells (dendritic cell, microfold cells), or through the invasion into the intestinal epithelial …

Background Common treatments for metastatic/unresectable HER2‐negative gastric cancer
include chemotherapy, immune checkpoint inhibitor monotherapy and chemotherapy plus …