MR-guided focused ultrasound in movement disorders and beyond: Lessons learned and new frontiers

E Natera-Villalba, MA Ruiz-Yanzi… - Parkinsonism & Related …, 2024 - Elsevier
The development of MR-guided focused ultrasound (MRgFUS) has provided a new
therapeutic tool for neuropsychiatric disorders. In contrast to previously available …

A systematic review comparing focused ultrasound surgery with radiosurgery for essential tremor

S Kondapavulur, AB Silva, AM Molinaro… - Neurosurgery, 2023 - journals.lww.com
BACKGROUND: Focused ultrasound (FUS-T) and stereotactic radiosurgery thalamotomy
(SRS-T) targeting the ventral intermediate nucleus are effective incisionless surgeries for …

[HTML][HTML] Comparative evaluation of tractography-based direct targeting and atlas-based indirect targeting of the ventral intermediate (Vim) nucleus in MRgFUS …

F Bruno, A Catalucci, M Varrassi, F Arrigoni… - Scientific Reports, 2021 - nature.com
To analyze and compare direct and indirect targeting of the Vim for MRgFUS thalamotomy.
We retrospectively evaluated 21 patients who underwent unilateral MRgFUS Vim ablation …

Deep‐learning based fully automatic segmentation of the globus pallidus interna and externa using ultra‐high 7 Tesla MRI

O Solomon, T Palnitkar, R Patriat, H Braun… - Human brain …, 2021 - Wiley Online Library
Deep brain stimulation (DBS) surgery has been shown to dramatically improve the quality of
life for patients with various motor dysfunctions, such as those afflicted with Parkinson's …

Focused ultrasound for functional neurosurgery

L Lev-Tov, DAN Barbosa, P Ghanouni… - Journal of Neuro …, 2022 - Springer
Introduction Brain lesioning is a fundamental technique in the functional neurosurgery world.
It has been investigated for decades and presented promising results long before novel …

[HTML][HTML] Technical comparison of treatment efficiency of magnetic resonance-guided focused ultrasound thalamotomy and pallidotomy in skull density ratio-matched …

AK Ahmed, S Guo, N Kelm, R Clanton… - Frontiers in …, 2022 - frontiersin.org
Objective MR-guided focused ultrasound (MRgFUS) is increasingly being used to treat
patients with essential tremor (ET) and Parkinson's disease (PD) with thalamotomy and …

MRI-based thermal dosimetry based on single-slice imaging during focused ultrasound thalamotomy

N McDannold, PJ White… - Physics in Medicine & …, 2020 - iopscience.iop.org
Transcranial MRI-guided focused ultrasound (MRgFUS) is a noninvasive thermal ablation
method approved for the treatment of essential tremor and tremor-dominant Parkinson's …

[HTML][HTML] Advancements in surgical treatments for Huntington disease: From pallidotomy to experimental therapies

LJY Kim, B Kundu, P Moretti, AM Lozano… - Neurotherapeutics, 2024 - Elsevier
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder
characterized by choreic movements, behavioral changes, and cognitive impairment. The …

Lesion 3D modeling in transcranial MR-guided focused ultrasound thalamotomy

M López-Aguirre, J Caballero-Insaurriaga… - Magnetic Resonance …, 2021 - Elsevier
Transcranial magnetic resonance-guided focused ultrasound (tMRgFUS) allows to perform
incisionless thermoablation of deep brain structures. This feature makes it a very useful tool …

The persistent value of lesions in psychiatric neurosurgery

H Abdulrazeq, AP Philips, R Sastry, PM Lauro… - The Lancet …, 2024 - thelancet.com
Neurosurgery for intractable psychiatric conditions has seen a resurgence with the
increasing use of deep brain stimulation (DBS). Although DBS promises reversible …