This review focuses on the neuronal and circuit mechanisms involved in the generation of
the theta (θ) rhythm and of its participation in behavior. Data have accumulated indicating …

Emotional learning and memory are functionally and dysfunctionally regulated by the
neuromodulatory state of the brain. While the role of excitatory and inhibitory neural circuits …

Before the onset of locomotion, the hippocampus undergoes a transition into an activity-state
specialized for the processing of spatially related input. This brain-state transition is …

Theta oscillations in the limbic system depend on the integrity of the medial septum. The
different populations of medial septal neurons (cholinergic and GABAergic) are assumed to …

We developed and applied a Cre-dependent, genetically modified rabies-based tracing
system to map direct synaptic connections to specific CA1 neuron types in the mouse …

The septo–hippocampal pathway adjusts CA1 network excitability to different behavioral
states and is crucially involved in theta rhythmogenesis. In the medial septum, cholinergic …

Spatial learning, including encoding and retrieval of spatial memories as well as holding
spatial information in working memory generally serving navigation under a broad range of …

Cholinergic septohippocampal projections from the medial septal area to the hippocampus
are proposed to have important roles in cognition by modulating properties of the …

Hippocampal theta oscillations orchestrate faster beta-to-gamma oscillations facilitating the
segmentation of neural representations during navigation and episodic memory. Supra …

The medial septum and diagonal band of Broca (MS-DBB) has an essential role for theta
rhythm generation in the hippocampus and is critical for learning and memory. The MS-DBB …