Immune checkpoint inhibitors in hepatocellular carcinoma: opportunities and challenges

X Liu, S Qin - The oncologist, 2019 - academic.oup.com
Hepatocellular carcinoma (HCC) is the most common malignancy worldwide, and is
especially common in China. A total of 70%–80% of patients are diagnosed at an advanced …

ABC transporters: regulation and association with multidrug resistance in hepatocellular carcinoma and colorectal carcinoma

MP Ceballos, JP Rigalli, LI Ceré… - Current medicinal …, 2019 - ingentaconnect.com
For most cancers, the treatment of choice is still chemotherapy despite its severe adverse
effects, systemic toxicity and limited efficacy due to the development of multidrug resistance …

β-Thujaplicin induces autophagic cell death, apoptosis, and cell cycle arrest through ROS-mediated Akt and p38/ERK MAPK signaling in human hepatocellular …

G Zhang, J He, X Ye, J Zhu, X Hu, M Shen, Y Ma… - Cell death & …, 2019 - nature.com
Hepatocellular carcinoma (HCC), a common liver malignancy worldwide, has high morbidity
and mortality. β-Thujaplicin, a tropolone derivative, has been used in some health-care …

Monitoring immune checkpoint regulators as predictive biomarkers in hepatocellular carcinoma

R Shrestha, P Prithviraj, M Anaka, KR Bridle… - Frontiers in …, 2018 - frontiersin.org
The global burden of hepatocellular carcinoma (HCC), one of the frequent causes of cancer-
related deaths worldwide, is rapidly increasing partly due to the limited treatment options …

The long non-coding RNA TP73-AS1 modulates HCC cell proliferation through miR-200a-dependent HMGB1/RAGE regulation

S Li, Y Huang, Y Huang, Y Fu, D Tang, R Kang… - Journal of experimental …, 2017 - Springer
Abstract Background P73 antisense RNA 1 T (non-protein coding), also known as TP73-
AS1, is a long non-coding RNA (lncRNA) which is involved in cell proliferation and the …

Protective effects of phenolics rich extract of ginger against Aflatoxin B1-induced oxidative stress and hepatotoxicity

AV Vipin, R Rao, NK Kurrey, AA KA… - Biomedicine & …, 2017 - Elsevier
Abstract Aflatoxin B 1 (AFB 1) is one of the predominant mycotoxin contaminant in food and
feed, causing oxidative stress and hepatotoxicity. Ginger phenolics have been reported for …

Clinical characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single center 14 years experience from China

C Wang, S Li - Medicine, 2019 - journals.lww.com
Clinical characteristics and prognosis of 2887 patients with... : Medicine Clinical
characteristics and prognosis of 2887 patients with hepatocellular carcinoma: A single …

Development of oral curcumin based on pH-responsive transmembrane peptide-cyclodextrin derivative nanoparticles for hepatoma

T Wei, Y Zhang, M Lei, Y Qin, Z Wang, Z Chen… - Carbohydrate …, 2022 - Elsevier
Herein, a pH-responsive cyclodextrin derivative (R6H4-CMβCD) with cell-penetrating ability
was successfully synthesized, and curcumin-loaded nanoparticles (R6H4-CMβCD@ CUR …

Epigenetic alterations caused by aflatoxin b1: a public health risk in the induction of hepatocellular carcinoma

RG Ferreira, MV Cardoso, KM De Souza Furtado… - Translational …, 2019 - Elsevier
Aflatoxin B1 (AFB1) is currently the most commonly studied mycotoxin due to its great
toxicity, its distribution in a wide variety of foods such as grains and cereals and its …

[HTML][HTML] Role of canonical Hedgehog signaling pathway in liver

L Gao, Z Zhang, P Zhang, M Yu… - International Journal of …, 2018 - ncbi.nlm.nih.gov
Hedgehog (Hh) signaling pathway plays an important role in embryonic development. It
becomes reactivated in many types of acute and chronic liver injuries. Hh signaling is …