Stem cell therapy: from idea to clinical practice

M Mousaei Ghasroldasht, J Seok, HS Park… - International journal of …, 2022 - mdpi.com
Regenerative medicine is a new and promising mode of therapy for patients who have
limited or no other options for the treatment of their illness. Due to their pleotropic therapeutic …

Biodistribution of mesenchymal stromal cells after administration in animal models and humans: a systematic review

M Sanchez-Diaz, MI Quiñones-Vico… - Journal of Clinical …, 2021 - mdpi.com
Mesenchymal Stromal Cells (MSCs) are of great interest in cellular therapy. Different routes
of administration of MSCs have been described both in pre-clinical and clinical reports …

Fluorescence microscopy—an outline of hardware, biological handling, and fluorophore considerations

SM Hickey, B Ung, C Bader, R Brooks, J Lazniewska… - Cells, 2021 - mdpi.com
Fluorescence microscopy has become a critical tool for researchers to understand biological
processes at the cellular level. Micrographs from fixed and live-cell imaging procedures …

The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer

J Heo, J Lee, YJ Nam, YH Kim, HD Yun, S Lee… - … & Molecular Medicine, 2022 - nature.com
Aberrant activation of embryogenesis-related molecular programs in urothelial bladder
cancer (BC) is associated with stemness features related to oncogenic dedifferentiation and …

[HTML][HTML] Mesenchymal stem cell transplantation alleviates experimental Sjögren's syndrome through IFN-β/IL-27 signaling axis

G Yao, J Qi, J Liang, B Shi, W Chen, W Li, X Tang… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Although mesenchymal stem cell (MSC) transplantation has been proved to be
an effective therapeutic approach to treat experimental Sjögren's syndrome (SS), the …

Phosphorylation of TFCP2L1 by CDK1 is required for stem cell pluripotency and bladder carcinogenesis

J Heo, BJ Noh, S Lee, HY Lee, YH Kim… - EMBO molecular …, 2020 - embopress.org
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic
dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms …

Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway

J Lim, J Heo, H Ju, JW Shin, YH Kim, S Lee, HY Yu… - Science …, 2020 - science.org
Glutathione (GSH), the most abundant nonprotein thiol functioning as an antioxidant, plays
critical roles in maintaining the core functions of mesenchymal stem cells (MSCs), which are …

Safety of human embryonic stem cell-derived mesenchymal stem cells for treating interstitial cystitis: a phase I study

JH Shin, CM Ryu, HY Yu, J Park… - Stem Cells …, 2022 - academic.oup.com
There are still no definite treatment modalities for interstitial cystitis (IC). Meanwhile, stem
cell therapy is rising as potential alternative for various chronic diseases. This study aimed to …

Activating transcription factor-2 supports the antioxidant capacity and ability of human mesenchymal stem cells to prevent asthmatic airway inflammation

H Ju, HD Yun, YH Kim, YJ Nam, S Lee, J Lee… - … & Molecular Medicine, 2023 - nature.com
Glutathione (GSH), an abundant nonprotein thiol antioxidant, participates in several
biological processes and determines the functionality of stem cells. A detailed …

[HTML][HTML] Management of postoperative pain after elective craniotomy: a prospective randomized controlled trial of a neurosurgical Enhanced Recovery after Surgery …

L Qu, B Liu, H Zhang, EW Sankey, W Chai… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Objective: To prospectively evaluate the efficacy of a neurosurgical enhanced recovery after
surgery (ERAS) protocol on the management of postoperative pain after elective …