The peritoneum defines a confined microenvironment, which is stable under normal
conditions, but is exposed to the damaging effect of infections, surgical injuries, and other …

Tissue damage frequently occurs. The immune system senses it and enforces homeostatic
responses that lead to regeneration and repair. The synthesis of acute phase molecules is …

Background Cellular sex has rarely been considered as a biological variable in preclinical
research, even when the pathogenesis of diseases with predictable sex differences is …

The human long pentraxin PTX3 has complex regulatory roles at the crossroad of innate
immunity, inflammation, and tissue repair. PTX3 can be produced by various cell types …

Dysfunctional elimination of cell debris, and the role of opsonins such as pentraxins, is of
interest regarding systemic lupus erythematosus (SLE) pathogenesis. Interferon (IFN)-α is …

Abstract Pentraxin-3 (PTX3) is a component of humoral innate immunity with essential
functions both in promotion and resolution of inflammation. We aimed to study the PTX3 in …

Prolonged exposure to hard metal dust results in hard metal lung disease (HMLD)
characterized by respiratory symptoms. Understanding the pathogenesis and pathological …

We evaluated the role of immunoglobulin binding protein 1 (IGBP1), a phosphoprotein
associated with the B cell receptor (BCR) complex, as a urine biomarker in lupus nephritis …

Die Parodontitis ist eine chronische Infektionserkrankung. An der Pathogenese dieser
Krankheit könnte nach aktuellen ätiologischen Modellen unter anderem eine ineffektive und …

Our recent data show that the IL-23–TH 17 axis controls the intrinsic inflammatory activity of
autoantibodies and thereby triggers the clinical onset of autoimmune arthritis in mice and …