The stability of gut microbiota is essential for the host's health. Parabacteroides spp., core
members of the human gut microbiota, have an average abundance of 1.27% in humans of …

Background: Recently discovered relationships between the gastrointestinal microbiome
and the brain have implications for psychiatric disorders, including major depressive …

The study explored the changes of a sulfated polysaccharide (SP) from Gracilaria
Lemaneiformis during simulated human digestive system. The results showed SP was …

Clostridioides difficile infection (CDI) is associated with high mortality rates among patients
with chronic illnesses. We aimed to identify avoidable risk factors to reduce the mortality rate …

Taihu Lake is one of the largest freshwater lakes in China and serves as an important
source for drinking water. This lake is suffering from eutrophication, cyanobacterial blooms …

We present a novel system that leverages curators in the loop to develop a dataset and
model for detecting structure features and functional annotations at residue-level from …

Cysteine proteases are among the most abundant hydrolytic enzymes produced by bacteria,
and this diverse family of proteins have significant biological roles in bacterial viability and …

Deep-sea hydrothermal vents offer unique habitats for heat tolerant enzymes with potential
new enzymatic properties. Here, we present the novel C11 protease globupain, which was …

Leishmania mexicana is one of the causative agents of cutaneous leishmaniasis in humans.
There is an urgent need to identify new drug targets to combat the disease. Cysteine …

Enterotoxigenic Bacteroides fragilis produces a secreted metalloprotease known as B.
fragilis toxin (BFT), which contributes to anaerobic sepsis, colitis, and colonic malignancy in …