Chemical modifications of transcripts with a 5′ cap occur in all organisms and function in
many aspects of RNA metabolism. To facilitate analysis of RNA caps, we developed a …

Nucleotides are at the heart of the most essential biological processes in the cell, be it as
key protagonists in the dogma of molecular biology or by regulating multiple metabolic …

Label-free spatial mapping of the noncovalent interactions of proteins in their tissue
environment has the potential to revolutionize life sciences research by providing …

Chemically modified oligonucleotides have advanced as important therapeutic tools as
reflected by the recent advent of mRNA vaccines and the FDA-approval of various siRNA …

Hericium erinaceus is an edible mushroom with diverse pharmaceutical applications.
Although this mushroom is an attractive source of natural products for cancer treatment, little …

Raphanus raphanistrum L. is an edible flowering plant that belongs to the Brassicaceae
family and is also known as wild radish. Recently, it was reported as a sustainable source of …

Alcohol consumption is a risk factor for the development of several cancers, including those
of the head and neck and the esophagus. The underlying mechanisms of alcohol-induced …

Modified nucleosides and nucleobases serve as potential diagnostic and prognostic
markers of various diseases, including cancer. These compounds are hydrophilic, but are …

Research on prebiotic chemistry and the origins of nucleic acids and proteins has
traditionally been focussed on only one or the other. However, if nucleotides and amino …

Levels of lipopolysaccharide (LPS), an essential glycolipid on the surface of most gram-
negative bacteria, are tightly controlled—making LPS synthesis a promising target for …