Ascorbic acid, as a one of the basic exogenous vitamins, occurs in the body in the form of
ascorbate, known for its strong antioxidant and anti-inflammatory properties. The presented …

In recent years, interest in the health effects of natural antioxidants has increased due to
their safety and applicability in cosmetic formulation. Nevertheless, efficacy of natural …

In mammals, DNA methylation in the form of 5-methylcytosine (5mC) can be actively
reversed to unmodified cytosine (C) through TET dioxygenase-mediated oxidation of 5mC to …

Mitochondria are not only the main energy supplier but are also the cell metabolic center
regulating multiple key metaborates that play pivotal roles in epigenetics regulation. These …

Vitamin C has been known for decades. It is common in everyday use as an element of the
diet, supplementation, and a preservative. For years, research has been conducted to …

Loss-of-function mutations in TET2 occur frequently in patients with clonal hematopoiesis,
myelodysplastic syndrome (MDS), and acute myeloid leukemia (AML) and are associated …

Stem-cell fate can be influenced by metabolite levels in culture, but it is not known whether
physiological variations in metabolite levels in normal tissues regulate stem-cell function in …

The primary function of the skin is to act as a barrier against insults from the environment,
and its unique structure reflects this. The skin is composed of two layers: the epidermal outer …

Abstract Vitamin C (Vit C) is a potent antioxidant with several applications in the cosmetic
and pharmaceutical fields. However, the biggest challenge in the utilization of Vit C is to …

Summary DNA N 6-methyladenine (6mA) modification is commonly found in microbial
genomes and plays important functions in regulating numerous biological processes in …