In many natural and clinical settings, bacteria are associated with some type of biotic or
abiotic surface that enables them to form biofilms, a multicellular lifestyle with bacteria …

Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Introduction: Biofilm formation represents a protected mode of growth that renders bacterial
cells less susceptible to antimicrobials and to killing by host immune effector mechanisms …

Hydrogels have become very popular due to their unique properties such as high water
content, softness, flexibility and biocompatibility. Natural and synthetic hydrophilic polymers …

Foot infections are the main disabling complication in patients with diabetes mellitus. These
infections can lead to lower-limb amputation, increasing mortality and decreasing the quality …

Chronic leg ulcers affect 1–2% of the general population and are related to increased
morbidity and health costs. Staphylococcus aureus and Pseudomonas aeruginosa are the …

Biofilms have conventionally been perceived as dense bacterial masses on surfaces,
following the five-step model of development. Initial biofilm research focused on surface …

A wound is damage of a tissue usually caused by laceration of a membrane, generally the
skin. Wound healing is accomplished in three stages in healthy individuals, including …

Acute infections caused by pathogenic bacteria have been studied extensively for well over
100 years. These infections killed millions of people in previous centuries, but they have …

Background: Despite a growing consensus that biofilms contribute to a delay in the healing
of chronic wounds, conflicting evidence pertaining to their identification and management …