Immune cell function and metabolism are closely linked. Many studies have now clearly
demonstrated that alterations in cellular metabolism influence immune cell function and that …

Immune cell infiltration in (white) adipose tissue (AT) during obesity is associated with the
development of insulin resistance. In AT, the main population of leukocytes are …

Abstract The theme of World Kidney Day 2017 is' kidney disease and obesity: healthy
lifestyle for healthy kidneys'. To mark this event, Nature Reviews Nephrology invited five …

Insulin resistance is a major cause of diabetes and is highly associated with adipose tissue
(AT) inflammation in obesity. RBP4, a retinol transporter, is elevated in insulin resistance …

Diabetes and obesity are worldwide health problems. White fat dynamically participates in
hormonal and inflammatory regulation. White adipose tissue is recognized as a multifactorial …

Adipose tissue (AT) regulates systemic insulin sensitivity through multiple mechanisms, and
alterations in de novo lipogenesis appear to contribute. Mice overexpressing GLUT4 in …

Obesity and insulin resistance have reached epidemic proportions. Obesogenic conditions
are associated with increased risk for the development of other comorbidities and obesity …

Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option
to treat a number of inflammatory conditions including COVID-19 acute respiratory distress …

Obesity is a pandemic disease affecting around 15% of the global population. Obesity is a
major risk factor for other conditions, such as type 2 diabetes and cardiovascular diseases …

T cell subsets differ in their metabolic requirements, and further insight into such differences
might be harnessed to selectively promote regulatory T cells (Tregs) for therapies in …