Transitions in gene regulatory processes responsible for the emergence of specialized cell types and spatiotemporal regulation of developmental signaling prior to the divergence of …
BA Ramirez-Corona, S Fruth, O Ofoegbu… - Genome …, 2021 - genome.cshlp.org
Transcription is controlled by interactions of cis-acting DNA elements with diffusible trans- acting factors. Changes in cis or trans factors can drive expression divergence within and …
Embryonic specification of the first body axis requires the formation of an Organizer, a group of cells with the ability to instruct fates in the surrounding tissue. The existence of organizing …
J Neiro, D Sridhar, A Dattani, A Aboobaker - bioRxiv, 2022 - biorxiv.org
Planarians have become an established model system to study regeneration and stem cells, but the regulatory elements in the genome remain almost entirely undescribed. Here, by …