[HTML][HTML] Stem cells in cancer therapy: opportunities and challenges

CL Zhang, T Huang, BL Wu, WX He, D Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Metastatic cancer cells generally cannot be eradicated using traditional surgical or
chemoradiotherapeutic strategies, and disease recurrence is extremely common following …

Stem cell-based therapies for cancer treatment: separating hope from hype

DW Stuckey, K Shah - Nature Reviews Cancer, 2014 - nature.com
Stem cell-based therapies are emerging as a promising strategy to tackle cancer. Multiple
stem cell types have been shown to exhibit inherent tropism towards tumours. Moreover …

Baculovirus: an insect-derived vector for diverse gene transfer applications

KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin… - Molecular Therapy, 2013 - cell.com
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

Emerging insights into barriers to effective brain tumor therapeutics

GF Woodworth, GP Dunn, EA Nance, J Hanes… - Frontiers in …, 2014 - frontiersin.org
There is great promise that ongoing advances in the delivery of therapeutics to the central
nervous system (CNS) combined with rapidly expanding knowledge of brain tumor patho …

[HTML][HTML] Suicide gene therapy for cancer–current strategies

P Zarogoulidis, K Darwiche, A Sakkas… - Journal of genetic …, 2013 - ncbi.nlm.nih.gov
Current cancer treatments may create profound iatrogenic outcomes. The adverse effects of
these treatments still remain, as the serious problems that practicing physicians have to …

Selective ablation of tumorigenic cells following human induced pluripotent stem cell-derived neural stem/progenitor cell transplantation in spinal cord injury

K Kojima, H Miyoshi, N Nagoshi… - Stem Cells …, 2019 - academic.oup.com
Tumorigenesis is an important problem that needs to be addressed in the field of human
stem/progenitor cell transplantation for the treatment of subacute spinal cord injury (SCI) …

Strategies in gene therapy for glioblastoma

A Kwiatkowska, MS Nandhu, P Behera, EA Chiocca… - Cancers, 2013 - mdpi.com
Glioblastoma (GBM) is the most aggressive form of brain cancer, with a dismal prognosis
and extremely low percentage of survivors. Novel therapies are in dire need to improve the …

Applications of innovation technologies for personalized cancer medicine: stem cells and gene-editing tools

A Hasanzadeh, A Ebadati, L Dastanpour… - ACS Pharmacology & …, 2023 - ACS Publications
Personalized medicine is a new approach toward safer and even cheaper treatments with
minimal side effects and toxicity. Planning a therapy based on individual properties causes …

Stem cell-based therapies for tumors in the brain: Are we there yet?

K Shah - Neuro-oncology, 2016 - academic.oup.com
Advances in understanding adult stem cell biology have facilitated the development of novel
cell-based therapies for cancer. Recent developments in conventional therapies (eg, tumor …

Neural stem cell therapy for cancer

JR Bagó, KT Sheets, SD Hingtgen - Methods, 2016 - Elsevier
Cancers of the brain remain one of the greatest medical challenges. Traditional surgery and
chemo-radiation therapy are unable to eradicate diffuse cancer cells and tumor recurrence …