Despite significant advances in the field of cancer immunotherapy, the majority of patients
still do not benefit from treatment and must rely on traditional therapies. Dendritic cells have …

Mobilizing antitumour immunity through vaccination potentially constitutes a powerful
anticancer strategy but has not yet provided robust clinical benefits in large patient …

Wnt/β-catenin signaling is a highly conserved pathway that regulates cell proliferation,
differentiation, apoptosis, stem cell self-renewal, tissue homeostasis, and wound healing …

T helper (Th) cells have received extensive attention owing to their indispensable roles in
anti-tumor immune responses. Th1 and Th2 cells are two key subsets of Th cells that exist in …

ABSTRACT Toll-like receptor 3 (TLR3) is a pattern recognition receptor that senses
exogenous (viral) as well as endogenous (mammalian) double-stranded RNA in …

Clinical progress in the field of HER2-positive breast cancer therapy has been dramatically
improved by understanding of the immune regulatory mechanisms of tumor …

Abstract Toll-like receptors 3 (TLR3) have been broadly studied among all TLRs over the
last few decades together with its agonists due to their contribution to cancer regression …

Simple Summary Breast cancer (BC) is a common malignancy with molecular diversity, ie,
heterogeneity. Aside from routine clinical treatments, such as chemotherapy and …

Currently, tumor treatment research still focuses on the cancer cells themselves, but the fact
that the immune system plays an important role in inhibiting tumor development cannot be …

Globally over 2 million women are diagnosed with breast cancer each year despite major
advances in detection and treatment of the disease. Breast cancer is comprised of several …