Effects of binary mixtures of benzo [a] pyrene, arsenic, cadmium, and lead on oxidative stress and toxicity in HepG2 cells

S Muthusamy, C Peng, JC Ng - Chemosphere, 2016 - Elsevier
Mixed contamination of benzo [a] pyrene (B [a] P), arsenic (As), cadmium (Cd), and lead (Pb)
is a major environmental and human health concern. The mixture toxicity data on these co …

Underlying mechanisms of cytotoxicity in HepG2 hepatocarcinoma cells exposed to arsenic, cadmium and mercury individually and in combination

W Cordier, M Yousaf, MJ Nell, V Steenkamp - Toxicology in Vitro, 2021 - Elsevier
Background Toxicity data regarding combinational exposure of humans to arsenic, cadmium
and mercury is scarce. Although hepatotoxicity has been reported, limited information is …

The binary, ternary and quaternary mixture toxicity of benzo[a]pyrene, arsenic, cadmium and lead in HepG2 cells

S Muthusamy, C Peng, JC Ng - Toxicology Research, 2016 - academic.oup.com
Polycyclic aromatic hydrocarbons (PAHs) and heavy metal/loid (s) are common
environmental pollutants. Toxicological interaction data on benzo [a] pyrene (B [a] P) and …

In vitro and in vivo approaches to assess atherosclerosis following exposure to low-dose mixtures of arsenic and cadmium

NK Subramaniam, N Gagnon, K Makhani… - Toxicology and Applied …, 2023 - Elsevier
Worldwide, millions of people are co-exposed to arsenic and cadmium. Environmental
exposure to both metals is linked with a higher risk of atherosclerosis. While studies have …

A high sensitivity micro format chemiluminescence enzyme inhibition assay for determination of Hg (II)

K Deshpande, RK Mishra, S Bhand - Sensors, 2010 - mdpi.com
A highly sensitive and specific enzyme inhibition assay based on alcohol oxidase (AlOx)
and horseradish peroxidase (HRP) for determination of mercury Hg (II) in water samples has …

[PDF][PDF] Evaluation of interaction and combined toxicity of polyaromatic hydrocarbons (PAHs) and metals using human cell-based bioassays

S Muthusamy - 2016 - core.ac.uk
Mixed contamination of polyaromatic hydrocarbons (PAHs) and metals are ubiquitous in the
environment. Some of the individual PAHs are known as human carcinogens, and metals …

Assessing the cyto-genotoxic impacts of un-neutralised and pH-neutralised acid mine drainage on the human breast cancer cell line, MCF-7

S Botha - 2015 - scholar.sun.ac.za
The use of toxicity tests to evaluate the quality of streams affected by mixtures such as acid
mine drainage (AMD), adds value to assessments whereby site-specific toxicological data …