How are we evaluating the cost-effectiveness of companion biomarkers for targeted cancer therapies? A systematic review

MK Seo, J Cairns - BMC cancer, 2021 - Springer
Background Despite the increasing economic assessment of biomarker-guided therapies,
no clear agreement exists whether existing methods are sufficient or whether different …

A practical guide to modeling and conducting a cost-effectiveness analysis of companion biomarker tests for targeted therapies using R: tutorial paper

MK Seo, M Strong - PharmacoEconomics, 2021 - Springer
Despite the increasing number of potential biomarkers identified in laboratories and
reported in much literature, the adoption of biomarkers routinely available in clinical practice …

[图书][B] Translations of Responsibility: Innovation Governance in Three European Regions

T Völker, R Slaattelid, R Strand - 2024 - library.oapen.org
In 2020, a group of European researchers got a European Union (EU) grant to do a project
called TRANSFORM. The objective of TRANSFORM was to integrate the principle of …

Controlling healthcare costs: just cost effectiveness or “just” cost effectiveness?

LM Fleck - Cambridge Quarterly of Healthcare Ethics, 2018 - cambridge.org
Meeting healthcare needs is a matter of social justice. Healthcare needs are virtually
limitless; however, resources, such as money, for meeting those needs, are limited. How …

Cancer beyond genetics: on the practical implications of downward causation

S Green - 2021 - direct.mit.edu
Discussions about reductionism and downward causation are often assumed to be primarily
of interest to phi los o phers. Often, however, the question of whether multiscale systems can …

Learning to see cancer in early detection research

IA Pérez - Medicine Anthropology Theory, 2021 - medanthrotheory.org
This article explores how scientists learn to detect 'pre-cancer', a new diagnostic category
defined by the risk of developing the titular disease. This process entails the observation of …

Game-changing? When biomarker discovery and novel forms of patient work meet

I Arteaga Pérez - Medical Anthropology, 2022 - Taylor & Francis
ABSTRACT I analyze the promised efficacy of Pembrolizumab, an immunotherapy regime
under clinical trial for patients with metastatic colorectal cancer. Drawing on anthropological …

Cancer beyond genetics: on the practical implications of downward causation

S Green - 2020 - philsci-archive.pitt.edu
Discussions about reductionism and downward causation are often assumed to be primarily
of interest to philosophers. Often, however, the question of whether multi-scale systems can …

[PDF][PDF] Precision Oncology in the News

MS Stenmarck, IW Nilsen - … : Issues at Stake and Matters of …, 2022 - library.oapen.org
Opportunities and costs of cancer treatment are on the increase (WHO Technical report
2018). Opportunities are often framed as medical and costs as economic. This creates an …

Kreft, forestillinger og sensasjonsjournalistikk. En analyse av sosiotekniske forestillinger om kreftforskning i møte med journalistiske nyhetsrammer

IW Nilsen - 2019 - bora.uib.no
Journalistikkens fremstilling av veivalg i forskning og teknologisk utvikling har tendenser til å
være langt på vei deterministiske. Måten disse forholdene fremstilles på kan ha store …