A systematic review of the factors influencing microbial colonization of the preterm infant gut

M Aguilar-Lopez, AM Dinsmoor, TTB Ho… - Gut …, 2021 - Taylor & Francis
Prematurity coupled with the necessary clinical management of preterm (PT) infants
introduces multiple factors that can interfere with microbial colonization. This study aimed to …

Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements

K Pärnänen, A Karkman, J Hultman, C Lyra… - Nature …, 2018 - nature.com
The infant gut microbiota has a high abundance of antibiotic resistance genes (ARGs)
compared to adults, even in the absence of antibiotic exposure. Here we study potential …

Intestinal dysbiosis and necrotizing enterocolitis: assessment for causality using Bradford Hill criteria

JB Fundora, P Guha, DR Shores, M Pammi… - Pediatric …, 2020 - nature.com
In recent years, several studies have shown that premature infants who develop NEC
frequently display enteric dysbiosis with increased Gram-negative bacteria for several days …

Whole genome sequencing and metagenomics for outbreak investigation, source attribution and risk assessment of food‐borne microorganisms

EFSA Panel on Biological Hazards (EFSA … - EFSA …, 2019 - Wiley Online Library
This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …

Capturing the antibiotic resistome of preterm infants reveals new benefits of probiotic supplementation

AK Guitor, EI Yousuf, AR Raphenya, EK Hutton… - Microbiome, 2022 - Springer
Background Probiotic use in preterm infants can mitigate the impact of antibiotic exposure
and reduce rates of certain illnesses; however, the benefit on the gut resistome, the …

Effects of probiotic supplementation on the gut microbiota and antibiotic resistome development in preterm infants

E Esaiassen, E Hjerde, JP Cavanagh… - Frontiers in …, 2018 - frontiersin.org
Objectives: In 2014 probiotic supplementation (Lactobacillus acidophilus and
Bifidobacterium longum subspecies infantis; InfloranⓇ) was introduced as standard of care …

Development of early life gut resistome and mobilome across gestational ages and microbiota-modifying treatments

A Bargheet, C Klingenberg, E Esaiassen, E Hjerde… - …, 2023 - thelancet.com
Background Gestational age (GA) and associated level of gastrointestinal tract maturation
are major factors driving the initial gut microbiota composition in preterm infants. Besides …

Potential elimination of human gut resistome by exploiting the benefits of functional foods

C Tsigalou, T Konstantinidis, E Stavropoulou… - Frontiers in …, 2020 - frontiersin.org
Recent advances in technology over the last decades have strived to elucidate the diverse
and abundant ecosystem of the human microbiome. The intestinal microbiota represents a …

Experimental support for multidrug resistance transfer potential in the preterm infant gut microbiota

M Hagbø, A Ravi, IL Angell, M Sunde, J Ludvigsen… - Pediatric …, 2020 - nature.com
Background There is currently a lack of experimental evidence for horizontal gene transfer
(HGT) mechanisms in the human gut microbiota. The aim of this study was therefore to …

Longitudinal gut bacterial colonization and its influencing factors of low birth weight infants during the first 3 months of life

C Chi, Y Xue, N Lv, Y Hao, R Liu, Y Wang… - Frontiers in …, 2019 - frontiersin.org
Establishment of low birth weight (LBW) infant gut microbiota may have lifelong implications
for the health of individuals. However, no longitudinal cohort studies have been conducted …