Abstract mRNA is packaged into ribonucleoprotein particles called mRNPs. A multitude of RNA-binding proteins as well as a host of associated proteins participate in the fate of …
CJ Herrmann, R Schmidt, A Kanitz, P Artimo… - Nucleic acids …, 2020 - academic.oup.com
Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly (A)) sites, alternative terminal exons account for much of the variation between human …
SC Kwon, H Yi, K Eichelbaum, S Föhr… - Nature structural & …, 2013 - nature.com
RNA-binding proteins (RBPs) have essential roles in RNA-mediated gene regulation, and yet annotation of RBPs is limited mainly to those with known RNA-binding domains. To …
Background RNA-protein interactions (RPIs) play important roles in a wide variety of cellular processes, ranging from transcriptional and post-transcriptional regulation of gene …
Messenger RNA decay is an essential step in gene expression to set mRNA abundance in the cytoplasm. The binding of proteins and/or noncoding RNAs to specific recognition …
ZA Shen, T Luo, YK Zhou, H Yu… - Briefings in …, 2021 - academic.oup.com
Noncoding RNAs (ncRNAs) play crucial roles in many biological processes. Experimental methods for identifying ncRNA–protein interactions (NPIs) are always costly and time …
RNA-protein complexes are essential in mediating important fundamental cellular processes, such as transport and localization. In particular, ncRNA-protein interactions play …
P Chatterji, AK Rustgi - Trends in molecular medicine, 2018 - cell.com
The intestinal epithelium is highly proliferative and consists of crypt invaginations that house stem cells and villus projections with differentiated cells. There exists a dynamic equilibrium …
RB Darnell - Annual review of neuroscience, 2013 - annualreviews.org
Neurons have their own systems for regulating RNA. Several multigene families encode RNA binding proteins (RNABPs) that are uniquely expressed in neurons, including the well …