The oxytocin/vasopressin ancestor molecule has been regulating reproductive and social
behaviors for more than 500 million years. In all mammals, oxytocin is the hormone …

The process of dog domestication likely involved at least two functional stages. The initial
stage occurred when subpopulations of wolves became synanthropes, benefiting from life …

The vertebrate nonapeptide vasotocin/vasopressin is evolutionarily highly conserved and
acts as neuromodulator and endocrine/paracrine signaling molecule. Circumstantial and …

The hypothalamus-pituitary-interrenal (HPI) and hypothalamus-sympathetic-chromaffin cell
(HSC) axes are involved in the regulation of the stress response in teleost. In this regard, the …

The process of canine domestication represents certainly one of the most interesting
questions that evolutionary biology aims to address. A “multiphase” view of this process is …

Neuropeptides are expressed in cell-specific patterns throughout mammalian brain.
Neuropeptide gene expression has been useful for clustering neurons by phenotype, based …

In zebrafish, estrogens produced in the ovaries via Cyp19a1a activity are required for both
sexual differentiation of the ovary during early development as well as maintenance of the …

The identification of structurally related hypothalamic hormones that regulate blood pressure
and diuresis (vasopressin, VP; CYFQNCPRG-NH2) or lactation and uterine contraction …

Oxytocin (OT) is a neuropeptide produced by hypothalamic neurons and is known to
modulate social behavior among other functions. Several experiments have shown that OT …

Vasopressin/oxytocin (VP/OT)-type neuropeptide is an ancient neurophysin-associated
neuropeptide and has been intensively studied to be involved in multiple physiological …