Nuclear targeting of therapeutics provides a strategy for enhancing efficacy of molecules
active in the nucleus and minimizing off-target effects.'Active'nuclear-directed transport and …

Over various scientific fields in biochemistry, amino acids have been highlighted in research
works. Protein, peptide-and amino acid-based drug delivery systems have proficiently …

Platinum (Pt) resistance in cancer almost inevitably occurs during clinical Pt-based
chemotherapy. The spontaneous nucleotide-excision repair of cancer cells is a …

Gene vectors have been extensively applied in various fields. However, the high economic
cost of gene vectors limits their development and application, and there is an urgent demand …

Graphene quantum dots (GQDs) are nano-sized graphene slices. With their small size,
lamellar and aromatic-ring structure, GQDs tend to enter into the cell nucleus and interfere …

Nucleic acids are emerging as powerful and functional biomaterials due to their molecular
recognition ability, programmability, and ease of synthesis and chemical modification …

The field of fluorescent nanodiamonds (FNDs) has advanced greatly over the past few
years. Though historically limited primarily to red fluorescence, the wavelengths available for …

Gene therapy is a promising therapeutic approach to treating different diseases; however,
the lack of platforms that can safely and efficiently carry desired genes to the targeted …

Nanodiamonds (ND) are chemically inert and stable owing to their sp3 covalent bonding
structure, but their surface sp2 graphitic carbons can be easily homogenized with diverse …

Owing to its aggressive biological behavior, the lack of specific targets, and the strong
therapeutic resistance of triple negative breast cancer (TNBC), current therapeutic strategies …