The biofilm life cycle: expanding the conceptual model of biofilm formation

K Sauer, P Stoodley, DM Goeres… - Nature Reviews …, 2022 - nature.com
Bacterial biofilms are often defined as communities of surface-attached bacteria and are
typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas …

Metal-based nanoparticles: Antibacterial mechanisms and biomedical application

D Franco, G Calabrese, SPP Guglielmino, S Conoci - Microorganisms, 2022 - mdpi.com
The growing increase in antibiotic-resistant bacteria has led to the search for new
antibacterial agents capable of overcoming the resistance problem. In recent years …

Biofilm dispersion

KP Rumbaugh, K Sauer - Nature Reviews Microbiology, 2020 - nature.com
The formation of microbial biofilms enables single planktonic cells to assume a multicellular
mode of growth. During dispersion, the final step of the biofilm life cycle, single cells egress …

Antibiotics versus biofilm: an emerging battleground in microbial communities

D Sharma, L Misba, AU Khan - Antimicrobial Resistance & Infection …, 2019 - Springer
Biofilm is a complex structure of microbiome having different bacterial colonies or single type
of cells in a group; adhere to the surface. These cells are embedded in extracellular …

Comprehensive review of antimicrobial activities of plant flavonoids

I Górniak, R Bartoszewski, J Króliczewski - Phytochemistry reviews, 2019 - Springer
Flavonoids are one of the largest classes of small molecular secondary metabolites
produced in different parts of the plant. They display a wide range of pharmacological and …

Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models

I Guzmán-Soto, C McTiernan, M Gonzalez-Gomez… - Iscience, 2021 - cell.com
Biofilm formation in living organisms is associated to tissue and implant infections, and it has
also been linked to the contribution of antibiotic resistance. Thus, understanding biofilm …

Biofilms: an emergent form of bacterial life

HC Flemming, J Wingender, U Szewzyk… - Nature Reviews …, 2016 - nature.com
Bacterial biofilms are formed by communities that are embedded in a self-produced matrix of
extracellular polymeric substances (EPS). Importantly, bacteria in biofilms exhibit a set …

Biofilm-related disease

JL Del Pozo - Expert review of anti-infective therapy, 2018 - Taylor & Francis
Introduction: Biofilm formation represents a protected mode of growth that renders bacterial
cells less susceptible to antimicrobials and to killing by host immune effector mechanisms …

Antibiotic resistance: turning evolutionary principles into clinical reality

DI Andersson, NQ Balaban, F Baquero… - FEMS microbiology …, 2020 - academic.oup.com
Antibiotic resistance is one of the major challenges facing modern medicine worldwide. The
past few decades have witnessed rapid progress in our understanding of the multiple factors …

Interactions of plasma-activated water with biofilms: Inactivation, dispersal effects and mechanisms of action

A Mai-Prochnow, R Zhou, T Zhang, K Ostrikov… - npj Biofilms and …, 2021 - nature.com
Biofilms have several characteristics that ensure their survival in a range of adverse
environmental conditions, including high cell numbers, close cell proximity to allow easy …