All cells, from prokaryotes to vertebrates, synthesize vast amounts of ribosomal RNA to
produce the several million new ribosomes per generation that are required to maintain the …

Introduction 3. General Background 3.1. The Nucleolus 3.2. Synthesis and Assembly of
Ribosomes 3.3. Proteins Associated with Ribosomes 4. rDNA Transcription 4.1. The rRNA …

The human ribosomal RNA promoter contains two distinct control elements (UCE and core)
both of which are recognized by the sequence-specific DNA binding protein UBF1, which …

The human rRNA promoter contains two distinct ciscontrol sequences, the core and
upstream control element (UCE), that serve as the target for binding cellular tram+ activating …

Like most eukaryotic rDNA promoters, the promoter for rDNA in Saccharomyces cerevisiae
consists of two elements: a core element, which is essential, and an upstream element …

A cell-free RNA polymerase I transcription system was used to evaluate the transcription
efficiency of 21 linker scanning mutations that span the human rRNA gene promoter. Our …

Although the typical, actively growing eukaryotic cell contains over 10 000 different
transcripts, half of its RNA synthetic capacity is devoted to the production of a single kind of …

How can trans-activators with the same DNA binding specificity direct different
transcriptional programs? The rRNA transcriptional apparatus offers a useful model system …

This article focuses on what is currently known about the regulation of transcription by RNA
polymerase I (pol I) in eukaryotic organisms at opposite ends of the evolutionary spectrum …

The structure of the rat homologue of the RNA polymerase I transcription factor UBF was
investigated. The sequence of the protein was deduced from the sequence of overlapping …