There is growing recognition that tuberculosis (TB) infection and disease exists as a
spectrum of states beyond the current binary classification of latent and active TB. Our aim …

The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …

Background Prevalence surveys show a substantial burden of subclinical (asymptomatic but
infectious) tuberculosis, from which individuals can progress, regress, or even persist in a …

Background Subclinical pulmonary tuberculosis, which presents without recognisable
symptoms, is frequently detected in community screening. However, the disease category is …

The rise of drug resistance has become a major obstacle in treating tuberculosis (TB),
significantly contributing to the increasing disease burden. Therefore, it is essential to study …

Traditional understanding of the risk of progression from Mycobacterium tuberculosis (Mtb)
infection to tuberculosis (TB) overlooks diverse presentations across a spectrum of disease …

The current active/latent paradigm of tuberculosis (TB) largely neglects the documented
spectrum of disease. Lack of consistency on definitions, terminology and diagnostic criteria …

Background People with radiographic evidence for pulmonary tuberculosis (TB), but
negative sputum cultures, have increased risk of developing culture-positive TB. Recent …

It is well known that people with TB can struggle with taking every single dose of such
lengthy treatment regimens, including due to side-effects [6]. Nonadherence (defined as …

Background Emerging evidence suggests that aberrant alternative splicing (AS) may play an
important role in tuberculosis (TB). However, current knowledge regarding the value of AS in …