Coronary microvascular dysfunction (CMD) encompasses several pathogenetic
mechanisms involving coronary microcirculation and plays a major role in determining …

Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Abstract N6-methyladenosine (m6A) is one of the most important epigenetic regulation of
RNAs, such as lncRNAs. However, the underlying regulatory mechanism of m6A in diabetic …

Diabetes causes lipid peroxide to accumulate within cardiomyocytes. Furthermore, lipid
peroxide buildup is a risk factor for ferroptosis. This study is aimed at examining whether …

In patients with diabetes, myocardial fibrosis may contribute to the pathogenesis of heart
failure and arrhythmogenesis, increasing ventricular stiffness and delaying conduction …

Diabetic cardiomyopathy (DCM) mainly refers to myocardial metabolic dysfunction caused
by high glucose, and hyperglycemia is an independent risk factor for cardiac function in the …

The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …

Diabetic cardiomyopathy (DCM) is a myocardial disease independent of other
cardiovascular diseases, such as coronary heart disease, hypertension, etc. Lipotoxicity is …

Ferroptosis is an iron-dependent cell death, which is characterized by iron overload and
lipid peroxidation. Ferroptosis is distinct from apoptosis, necroptosis, autophagy, and other …

Background: Type 2 diabetes mellitus (T2DM) is associated with a higher risk for heart
failure (HF). The impact of a lifestyle intervention and changes in cardiorespiratory fitness …