Polymersome-based protein drug delivery–quo vadis?

MG Gouveia, JP Wesseler, J Ramaekers… - Chemical Society …, 2023 - pubs.rsc.org
Protein-based therapeutics are an attractive alternative to established therapeutic
approaches and represent one of the fastest growing families of drugs. While many of these …

Polymer vesicles: Mechanism, preparation, application, and responsive behavior

Y Zhu, B Yang, S Chen, J Du - Progress in Polymer Science, 2017 - Elsevier
Polymer vesicles, also known as polymersomes, are finding increasing applications in
biomedical field, including drug delivery, gene therapy, magnetic resonance imaging …

Stimuli-responsive polymersomes for biomedical applications

X Hu, Y Zhang, Z Xie, X Jing, A Bellotti, Z Gu - Biomacromolecules, 2017 - ACS Publications
Polymersomes, the structural analogues of liposomes, are hollow structures enclosed by a
bilayer membrane made from amphiphilic copolymers. Polymersomes have been proposed …

Engineering functional polymer capsules toward smart nanoreactors

J Gaitzsch, X Huang, B Voit - Chemical reviews, 2016 - ACS Publications
The design and construction of integrated chemical ensembles for studying complex
biological systems is attracting considerable interest in a wide range of research …

Polymersomes for therapeutic delivery of protein and nucleic acid macromolecules: from design to therapeutic applications

S Iqbal, M Blenner, A Alexander-Bryant… - …, 2020 - ACS Publications
Macromolecule-based therapeutic agents, particularly proteins, antigens, monoclonal
antibodies, transcription factors, nucleic acids, and gene editing enzymes, have the potential …

Polymersome-based drug-delivery strategies for cancer therapeutics

T Anajafi, S Mallik - Therapeutic delivery, 2015 - Taylor & Francis
Polymersomes are stable vesicles prepared from amphiphilic polymers and are more stable
compared with liposomes. Although these nanovesicles have many attractive properties for …

Engineering polymersomes for diagnostics and therapy

J Leong, JY Teo, VK Aakalu, YY Yang… - Advanced healthcare …, 2018 - Wiley Online Library
Engineered polymer vesicles, termed as polymersomes, confer a flexibility to control their
structure, properties, and functionality. Self‐assembly of amphiphilic copolymers leads to …

Polymerization-induced polymersome fusion

S Varlas, R Keogh, Y Xie, SL Horswell… - Journal of the …, 2019 - ACS Publications
The dynamic interactions of membranes, particularly their fusion and fission, are critical for
the transmission of chemical information between cells. Fusion is primarily driven by …

Polymerization-Induced Self-Assembly with Assistance of Aromatic Interactions Facilitates the Formation of Polymeric Nanotubes

RM Zhu, ZX Chang, WJ Zhang, CY Hong - Macromolecules, 2023 - ACS Publications
Polymerization-induced self-assembly (PISA) has been demonstrated to be a powerful
strategy for producing polymeric nano-objects. Polymeric nanotubes with hollow and …

Non-spherical particles for targeted drug delivery

J Chen, NE Clay, N Park, H Kong - Chemical engineering science, 2015 - Elsevier
Nano-and microparticles loaded with various bioimaging contrast agents or therapeutic
molecules have been increasingly used for the diagnosis and treatment of diseases and …