Diabetic vascular diseases: molecular mechanisms and therapeutic strategies

Y Li, Y Liu, S Liu, M Gao, W Wang, K Chen… - Signal transduction and …, 2023 - nature.com
Vascular complications of diabetes pose a severe threat to human health. Prevention and
treatment protocols based on a single vascular complication are no longer suitable for the …

Sex differences in peripheral artery disease

M Pabon, S Cheng, SE Altin, SS Sethi… - Circulation …, 2022 - Am Heart Assoc
Peripheral artery disease (PAD) is a prevalent condition that confers substantial morbidity
and mortality and remains underdiagnosed as well as undertreated in the overall …

Health disparities in peripheral artery disease: a scientific statement from the American Heart Association

MA Allison, DG Armstrong, PP Goodney… - Circulation, 2023 - Am Heart Assoc
Peripheral artery disease (PAD) affects 200 million individuals worldwide. In the United
States, certain demographic groups experience a disproportionately higher prevalence and …

Smoking and the pathophysiology of peripheral artery disease

W Wang, T Zhao, K Geng, G Yuan, Y Chen… - Frontiers in …, 2021 - frontiersin.org
Smoking is one of the most important preventable factors causing peripheral artery disease
(PAD). The purpose of this review is to comprehensively analyze and summarize the …

Approaches to peripheral artery disease in diabetes: are there any differences?

A Achim, A Stanek, C Homorodean, M Spinu… - International Journal of …, 2022 - mdpi.com
Peripheral artery disease (PAD) increases the risk of diabetes, while diabetes increases the
risk of PAD, and certain symptoms in each disease increase the risk of contracting the other …

Medial arterial calcification: a significant and independent contributor of peripheral artery disease

C St. Hilaire - Arteriosclerosis, thrombosis, and vascular biology, 2022 - Am Heart Assoc
Over 200 million individuals worldwide are estimated to have peripheral artery disease
(PAD). Although the term peripheral can refer to any outer branch of the vasculature, the …

A viscoelastic constitutive model for human femoropopliteal arteries

W Zhang, M Jadidi, SA Razian, GA Holzapfel… - Acta biomaterialia, 2023 - Elsevier
High failure rates present challenges for surgical and interventional therapies for peripheral
artery disease of the femoropopliteal artery (FPA). The FPA's demanding biomechanical …

Microvascular dysfunction and neurovascular uncoupling are exacerbated in peripheral artery disease, increasing the risk of cognitive decline in older adults

CD Owens, P Mukli, T Csipo, A Lipecz… - American Journal …, 2022 - journals.physiology.org
Peripheral artery disease (PAD) is a vascular pathology with high prevalence among the
aging population. PAD is associated with decreased cognitive performance, but the …

[HTML][HTML] Exercise therapy in the management of peripheral arterial disease

AO Hallak, FZ Hallak, YO Hallak, OO Hallak… - … : Innovations, Quality & …, 2023 - Elsevier
The incidence and prevalence of peripheral artery disease (PAD) are increasing globally
and have a marked economic burden in the United States. The American Heart …

The RGD-modified self-assembling D-form peptide hydrogel enhances the therapeutic effects of mesenchymal stem cells (MSC) for hindlimb ischemia by promoting …

P Jia, X Zhao, Y Liu, M Liu, Q Zhang, S Chen… - Chemical Engineering …, 2022 - Elsevier
Mesenchymal stem cell (MSC)-based therapy was an ideal strategy for therapeutic
angiogenesis in ischemic tissues. However, limitations such as heterogeneous …