Self-emulsifying formulations to augment therapeutic efficacy of nutraceuticals: From concepts to clinic

RK Dhritlahre, Y Padwad, A Saneja - Trends in Food Science & …, 2021 - Elsevier
Background Nutraceuticals often referred as medicinally or nutritionally functional foods has
drawn extensive attention in recent years because of their wide array of pharmacological …

Comparison of three different aqueous microenvironments for enhancing oral bioavailability of sildenafil: solid self-nanoemulsifying drug delivery system, amorphous …

JS Kim, F Din, SM Lee, DS Kim, MR Woo… - International journal …, 2021 - Taylor & Francis
Background The purpose of this study was to screen various drug delivery systems for
improving the aqueous solubility and oral bioavailability of sildenafil. Three representative …

Comparison of the physicochemical properties, aqueous solubility, and oral bioavailability of rivaroxaban-loaded high-pressure homogenised and Shirasu porous …

MJ Choi, JS Kim, H Yu, MR Woo, JE Choi… - Journal of Molecular …, 2022 - Elsevier
This study aimed to compare high-pressure homogenization (HPH) and Shirasu porous
glass (SPG) membrane emulsification for enhancing the oral bioavailability of rivaroxaban …

Quality by design-based development of solid self-emulsifying drug delivery system (SEDDS) as a potential carrier for oral delivery of lysozyme

M Šahinović, A Hassan, K Kristó, G Regdon Jr… - Pharmaceutics, 2023 - mdpi.com
For many years, researchers have been making efforts to find a manufacturing technique, as
well as a drug delivery system, that will allow for oral delivery of biopharmaceuticals to their …

17-α hydroxyprogesterone nanoemulsifying preconcentrate-loaded vaginal tablet: A novel non-invasive approach for the prevention of preterm birth

M Patki, K Giusto, S Gorasiya, SE Reznik, K Patel - Pharmaceutics, 2019 - mdpi.com
Preterm birth (PTB) is a major cause of infant mortality in the United States and around the
globe. Makena®—once-a-week intramuscular injection of 17-α Hydroxyprogesterone …

The importance of the coating material type and amount in the preparation of liquisolid systems based on magnesium aluminometasilicate carrier

B Vraníková, P Svačinová, J Marushka… - European Journal of …, 2021 - Elsevier
Albeit the preparation of liquisolid systems represents an innovative approach to enhance
the dissolution of poorly soluble drugs, their broader utilization is still limited mainly due to …

Formulation and in vivo evaluation of a solid self-emulsifying drug delivery system using oily liquid tocotrienols as model active substance

YZ Lee, EK Seow, SC Lim, KH Yuen… - Pharmaceutics, 2021 - mdpi.com
Self-emulsifying drug delivery systems (SEDDS) can improve the oral bioavailability of
poorly water-soluble drugs. Solid self-emulsifying drug delivery systems (s-SEDDS) offer …

Enhancing oral absorption of poorly water-soluble herb (Kaempferia parviflora) extract using self-nanoemulsifying formulation

P Chairuk, S Tubtimsri, C Jansakul… - Pharmaceutical …, 2020 - Taylor & Francis
Kaempferia parviflora, a medicinal herb, treats hypertension and promotes longevity with
good health and well-being. Its bioactive component is poorly soluble in water, resulting in …

Comparison of two self-nanoemulsifying drug delivery systems using different solidification techniques for enhanced solubility and oral bioavailability of poorly water …

MR Woo, S Woo, YW Bak, S Cheon, JS Kim… - Colloids and Surfaces B …, 2024 - Elsevier
In this study, we aimed to develop a solid self-nanoemulsifying drug delivery system (S-
SNEDDS) and a solid self-nanoemulsifying granule system (S-SNEGS) to enhance the …

Sublingual indocyanine green films for non-invasive swallowing assessment and inflammation detection through NIR/SWIR optical imaging

AOR Beringhs, SP Singh, TA Valdez, X Lu - Scientific Reports, 2020 - nature.com
Indocyanine green (ICG) is the most commonly used FDA-approved agent for clinical optical
imaging, administered through injections only, due to its poor membrane permeability …