Neuroinflammatory mechanisms of mitochondrial dysfunction and neurodegeneration in glaucoma

JN Duarte - Journal of Ophthalmology, 2021 - Wiley Online Library
The exact mechanism of retinal ganglion cell loss in the pathogenesis of glaucoma is yet to
be understood. Mitochondrial damage‐associated molecular patterns (DAMPs) resulting …

Glaucoma: from pathogenic mechanisms to retinal glial cell response to damage

JA Fernández-Albarral, AI Ramírez… - Frontiers in Cellular …, 2024 - frontiersin.org
Glaucoma is a neurodegenerative disease of the retina characterized by the irreversible loss
of retinal ganglion cells (RGCs) leading to visual loss. Degeneration of RGCs and loss of …

CDED-Net: Joint segmentation of optic disc and optic cup for glaucoma screening

M Tabassum, TM Khan, M Arsalan, SS Naqvi… - IEEE …, 2020 - ieeexplore.ieee.org
Glaucoma is an eye disease that can cause loss of vision by damaging the optic nerve. It is
the world's second leading cause of blindness after cataracts. Early diagnosis of glaucoma …

An automated glaucoma screening system using cup-to-disc ratio via simple linear iterative clustering superpixel approach

NA Mohamed, MA Zulkifley, WMDW Zaki… - … Signal Processing and …, 2019 - Elsevier
Glaucoma is an ocular disease caused by damaged optic nerve head (ONH) due to high
intraocular pressure (IOP) within the eyeball. Usually, glaucoma patients will not realize the …

[HTML][HTML] The role of microglia in the progression of glaucomatous neurodegeneration-a review

HL Zeng, JM Shi - International journal of ophthalmology, 2018 - ncbi.nlm.nih.gov
Glaucoma is a serious leading cause of irreversible blindness worldwide. Reducing
intraocular pressure (IOP) does not always stop glaucomatous neurodegeneration and the …

Normal tension glaucoma: from the brain to the eye or the inverse?

HJ Zhang, XS Mi, KF So - Neural Regeneration Research, 2019 - journals.lww.com
Glaucoma is a chronic, progressive optic neuropathy characterized by the loss of peripheral
vision first and then central vision. Clinically, normal tension glaucoma is considered a …

EDDense-Net: Fully Dense Encoder Decoder Network for Joint Segmentation of Optic Cup and Disc

M Mehmood, K Naveed, K Aurangzeb, HA Khan… - arXiv preprint arXiv …, 2023 - arxiv.org
Glaucoma is an eye disease that causes damage to the optic nerve, which can lead to visual
loss and permanent blindness. Early glaucoma detection is therefore critical in order to …

Th1 cells contribute to retinal ganglion cell loss in glaucoma in a VCAM-1-dependent manner

C He, K Peng, X Zhu, Z Wang, W Xiu, G Zhang… - Journal of …, 2024 - Springer
Glaucoma is a complex neurodegenerative disorder characterized by the progressive loss of
retinal ganglion cells (RGC) and optic nerve axons, leading to irreversible visual impairment …

Is glaucoma an autoimmune disease?

D Wakefield, G Wildner - Clinical & Translational Immunology, 2020 - Wiley Online Library
There is increasing evidence from animal and human studies that glaucoma is an
autoimmune disease. Evidence for this hypothesis includes the fact that antibodies as well …

Alterations in peripheral B cell subsets correlate with the disease severity of human glaucoma

L Yu, Y Chen, X Xu, Q Dong, W Xiu… - Journal of …, 2021 - Taylor & Francis
Background Glaucoma is a group of retinal neurodegenerative diseases causing
irreversible visual impairment. The pathogenesis of this disease is complicated. Studies …