Cardiac arrhythmias are among the leading causes of mortality. They often arise from
alterations in the electrophysiological properties of cardiac cells and their underlying ionic …

Brugada syndrome (BrS) is a rare hereditary arrhythmia disorder, with a distinctive ECG
pattern, correlated with an increased risk of ventricular arrhythmias and sudden cardiac …

Background Brugada syndrome is an inherited arrhythmic disease associated with major
arrhythmic events (MAE). Risk predictive scores were previously developed with various …

In this work, we reported a computational study to quantitatively determine the individual
contributions of three candidate arrhythmic factors associated with Brugada Syndrome. In …

Aims Sick sinus syndrome (SSS) and atrial fibrillation (AF) frequently coexist and show a
bidirectional relationship. This systematic review and meta-analysis aimed to decipher the …

The Transient Receptor Potential Melastatin 4 (TRPM4) is a transmembrane N‐glycosylated
ion channel that belongs to the large family of TRP proteins. It has an equal permeability to …

In this work, we present a computational study of the Brugada Syndrome (BrS) phenotype
aimed at investigating the main factors contributing to the development of arrhythmias. We …

Background: This study examined the clinical characteristics, genetic basis, healthcare
utilisation and costs of catecholaminergic ventricular tachycardia (CPVT) patients from a …

Background Twelve‐lead electrocardiogram (ECG) is a common and inexpensive tool for
the diagnostic workup of patients with suspected cardiovascular disease, both in clinical and …

The synchronization of the electrical and mechanical coupling assures the physiological
pump function of the heart, but life-threatening pathologies may jeopardize this equilibrium …