[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Regulation of long-chain polyunsaturated fatty acid biosynthesis in teleost fish

D Xie, C Chen, Y Dong, C You, S Wang… - Progress in Lipid …, 2021 - Elsevier
Abstract Omega-3 (n-3) long-chain polyunsaturated fatty acids (LC-PUFA, C 20-24),
including eicosapentaenoic acid (EPA, 20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n …

Evolution and Functional Characteristics of the Novel elovl8 That Play Pivotal Roles in Fatty Acid Biosynthesis

S Sun, Y Wang, PT Goh, M Lopes-Marques… - Genes, 2021 - mdpi.com
Elongation of very long-chain fatty acid (Elovl) proteins are key enzymes that catalyze the
rate-limiting step in the fatty acid elongation pathway. The most recently discovered member …

Transcriptome Profiling Revealed Basis for Growth Heterosis in Hybrid Tilapia (Oreochromis niloticus ♀ × O. aureus ♂)

J Zhu, Z Zou, D Li, W Xiao, J Yu, B Chen, L Xue… - Fishes, 2022 - mdpi.com
Hybrid tilapia were produced from hybridization of Nile tilapia (Oreochromis niloticus) and
blue tilapia (O. aureus). Comparative transcriptome analysis was carried out on the liver of …

Association Analysis between Genetic Variants of elovl5a and elovl5b and Poly-Unsaturated Fatty Acids in Common Carp (Cyprinus carpio)

Y Zhang, QS Li, YQ Ye, Q Wang, XQ Sun, R Zhao, JT Li - Biology, 2022 - mdpi.com
Simple Summary PUFAs have an essential impact on human health, but their availability
constitutes a critical bottleneck in food production. Although fish is the traditional source of …

Molecular characterization of fad6 gene and its transcriptional changes in response to different initial diets and nutritional status in yellow catfish (Pelteobagrus …

B Zhou, XY Wei, ZY Wen, B Wang, YY Zhao… - Frontiers in Marine …, 2024 - frontiersin.org
Fatty acid desaturases (FADs) are rate-limiting enzymes for the biosynthesis of highly
unsaturated fatty acids (HUFAs). As a new member of the FAD family, Fad6 and its roles …

Long-chain polyunsaturated fatty acid biosynthesis in a land-crab with advanced terrestrial adaptations: molecular cloning and functional characterization of two fatty …

SY Ting, NS Lau, KK Sam, M Janaranjani… - … and Physiology Part B …, 2022 - Elsevier
Depending on the presence and activities of the front-end fatty acyl desaturases and
elongation of very long-chain fatty acid (Elovl) enzymes, animals have different capacities for …

The Promoter SNPs Were Associated with Both the Contents of Poly-Unsaturated Fatty Acids (PUFAs) and the Expressions of PUFA-Related Genes in Common Carp

Y Zhang, ZM Xu, Q Wang, QS Li, XQ Sun, JT Li - Biology, 2023 - mdpi.com
Simple Summary Fish is an important PUFA source for human diet. Much research has
focused on increasing the PUFA products of fish. Improving the biosynthesis of PUFAs …

The Malaysian Mahseer, Tor tambroides possess all required biosynthesis enzymes for the conversion of C18 polyunsaturated fatty acids to long-chain …

KK Sam, P Merosha, M Janaranjani, I Athirah… - Aquaculture, 2021 - Elsevier
Abstract The Malaysian mahseer (Tor tambroides) is an iconic and highly-priced freshwater
large cyprinid with a natural dietary preference towards riverine fruits. Previous works …

A complete inventory of long-chain polyunsaturated fatty acid biosynthesis pathway enzymes in the miniaturized cyprinid Paedocypris micromegethes

KK Sam, NS Lau, MK Kuah, EA Lading… - Fish Physiology and …, 2022 - Springer
The capacity for long-chain polyunsaturated fatty acid (LC-PUFA) biosynthesis activity in a
species depends on the enzymatic activities of fatty acyl desaturase (Fads) and elongation …