Hepatitis C virus (HCV) infection and its complications have been the major cause of
cirrhosis and its complications for several decades in the Western world. Until recently …

Innate immunity includes a cellular and a humoral arm. PTX3 is a fluid-phase pattern
recognition molecule conserved in evolution which acts as a key component of humoral …

Pentraxins are a superfamily of fluid phase pattern recognition molecules conserved in
evolution and characterized by a cyclic multimeric structure. C-reactive protein (CRP) and …

Emerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an
essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis …

The pentraxin is a superfamily of proteins with the same domain known as the pentraxin
domain at C-terminal. This family has two subgroups, namely; short pentraxins (C-reactive …

Purpose Up to 1% of all men experience azoospermia, a condition of complete absence of
sperm in the semen. The mechanisms and genes involved in spermatogenesis are mainly …

The diagnosis of neurodegenerative disorders is often challenging due to the lack of
diagnostic tools, comorbidities and shared pathological manifestations. Synaptic dysfunction …

The atherosclerotic vascular disease is a cardiovascular continuum in which the main role is
attributed to atherosclerosis, from its appearance to its associated complications. The …

The innate immune system constitutes the first line of defence against microorganisms and
plays a primordial role in the activation and regulation of adaptive immunity. The innate …

Research in the last two decades has identified many synaptic organizers in the central
nervous system that directly regulate the assembly of pre-and/or postsynaptic molecules …