Long noncoding RNAs: a missing link in osteoporosis

AM Silva, SR Moura, JH Teixeira, MA Barbosa… - Bone research, 2019 - nature.com
Osteoporosis is a systemic disease that results in loss of bone density and increased
fracture risk, particularly in the vertebrae and the hip. This condition and associated …

Long noncoding RNAs in host–pathogen interactions

F Agliano, VA Rathinam, AE Medvedev, SK Vanaja… - Trends in …, 2019 - cell.com
Long noncoding RNAs (lncRNAs) are key molecules that regulate gene expression in a
variety of organisms. LncRNAs can drive different transcriptional and post-transcriptional …

Evolutionarily conserved long non-coding RNA regulates gene expression in cytokine storm during COVID-19

OB Morenikeji, K Bernard, E Strutton… - … in bioengineering and …, 2021 - frontiersin.org
Coronavirus is a family of viruses including alpha-, beta-, gamma-, delta-coronaviruses. Only
alpha-and betacoronaviruses have been observed to infect humans. Past outbreaks of …

Molecular pathways identified from single nucleotide polymorphisms demonstrate mechanistic differences in systemic lupus erythematosus patients of Asian and …

KA Owen, KA Bell, A Price, P Bachali, H Ainsworth… - Scientific reports, 2023 - nature.com
Systemic lupus erythematosus (SLE) is a multi-organ autoimmune disorder with a prominent
genetic component. Individuals of Asian-Ancestry (AsA) disproportionately experience more …

Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis

S Thériault, C Dina, D Messika-Zeitoun… - Circulation: Genomic …, 2019 - Am Heart Assoc
Background: Calcific aortic valve stenosis (CAVS) is a frequent and life-threatening
cardiovascular disease for which there is currently no medical treatment available. To date …

[HTML][HTML] Long non-coding RNA HOTAIR in central nervous system disorders: new insights in pathogenesis, diagnosis, and therapeutic potential

J Wang, J Zhao, P Hu, L Gao, S Tian… - Frontiers in Molecular …, 2022 - frontiersin.org
Central nervous system (CNS) disorders, such as ischemic stroke, neurodegenerative
diseases, multiple sclerosis, traumatic brain injury, and corresponding neuropathological …

[HTML][HTML] Immunomodulation as therapy for fungal infection: are we closer?

QH Sam, WS Yew, CJ Seneviratne… - Frontiers in …, 2018 - frontiersin.org
Invasive fungal disease (IFD) causes significant morbidity in immunocompromised patients
due to their weakened immune system. Immunomodulatory therapy, in synergy with existing …

[HTML][HTML] Genetic resilience in chickens against bacterial, viral and protozoal pathogens

H Gul, G Habib, IM Khan, SU Rahman… - Frontiers in Veterinary …, 2022 - frontiersin.org
Genome makes an individual breed unique with distinctive characteristics that pass from
one generation to the next. The allelic heterogeneity of a certain breed gives a different …

HOTAIR but not ANRIL long non‐coding RNA contributes to the pathogenesis of multiple sclerosis

M Pahlevan Kakhki, A Nikravesh… - …, 2018 - Wiley Online Library
Studies have revealed that dysregulation in gene expression is one of the main aspects of
multiple sclerosis (MS) pathogenesis. Although the molecular pathways underlying the …

[HTML][HTML] Identification of a TLR-induced four-lncRNA signature as a novel prognostic biomarker in esophageal carcinoma

J Liu, Y Wang, Y Chu, R Xu, D Zhang… - Frontiers in Cell and …, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) have emerged as key regulators of Toll-like receptor
(TLR) signaling to control innate immunity, and this regulatory mechanism has recently been …