A review and database of snake venom proteomes

T Tasoulis, GK Isbister - Toxins, 2017 - mdpi.com
Advances in the last decade combining transcriptomics with established proteomics
methods have made possible rapid identification and quantification of protein families in …

[HTML][HTML] Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms

B Lomonte, JJ Calvete - Journal of Venomous Animals and Toxins …, 2017 - SciELO Brasil
This work offers a general overview on the evolving strategies for the proteomic analysis of
snake venoms, and discusses how these may be combined through diverse experimental …

Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

L Ledsgaard, J Wade, TP Jenkins, K Boddum… - Nature …, 2023 - nature.com
Snakebite envenoming continues to claim many lives across the globe, necessitating the
development of improved therapies. To this end, broadly-neutralizing human monoclonal …

Convergent evolution of pain-inducing defensive venom components in spitting cobras

TD Kazandjian, D Petras, SD Robinson, J van Thiel… - Science, 2021 - science.org
Convergent evolution provides insights into the selective drivers underlying evolutionary
change. Snake venoms, with a direct genetic basis and clearly defined functional …

High-throughput proteomics and in vitro functional characterization of the 26 medically most important elapids and vipers from sub-Saharan Africa

GTT Nguyen, C O'Brien, Y Wouters, L Seneci… - …, 2022 - academic.oup.com
Venomous snakes are important parts of the ecosystem, and their behavior and evolution
have been shaped by their surrounding environments over the eons. This is reflected in their …

Venomics, lethality and neutralization of Naja kaouthia (monocled cobra) venoms from three different geographical regions of Southeast Asia

KY Tan, CH Tan, SY Fung, NH Tan - Journal of proteomics, 2015 - Elsevier
Previous studies showed that venoms of the monocled cobra, Naja kaouthia from Thailand
and Malaysia are substantially different in their median lethal doses. The intraspecific venom …

Intrageneric cross-reactivity of monospecific rabbit antisera against venoms of the medically most important Naja spp. African snakes

A Gómez, A Sánchez, G Durán, M Villalta… - PLOS Neglected …, 2023 - journals.plos.org
Background Envenomations by African snakes represent a high burden in the sub-Sahara
region. The design and fabrication of polyspecific antivenoms with a broader effectiveness …

Proteomic analysis to unravel the complex venom proteome of eastern India Naja naja: Correlation of venom composition with its biochemical and pharmacological …

S Dutta, A Chanda, B Kalita, T Islam, A Patra… - Journal of …, 2017 - Elsevier
The complex venom proteome of the eastern India (EI) spectacled cobra (Naja naja) was
analyzed using tandem mass spectrometry of cation-exchange venom fractions. About 75 …

Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
Venomic research, powered by techniques adapted from proteomics, transcriptomics, and
genomics, seeks to unravel the diversity and complexity of venom through which knowledge …

Next-generation snake venomics: protein-locus resolution through venom proteome decomplexation

JJ Calvete - Expert review of proteomics, 2014 - Taylor & Francis
Venom research has been continuously enhanced by technological advances. High-
throughput technologies are changing the classical paradigm of hypothesis-driven research …