Inflammation, fracture and bone repair

F Loi, LA Córdova, J Pajarinen, T Lin, Z Yao… - Bone, 2016 - Elsevier
The reconstitution of lost bone is a subject that is germane to many orthopedic conditions
including fractures and non-unions, infection, inflammatory arthritis, osteoporosis …

Modulation of the inflammatory response for enhanced bone tissue regeneration

PM Mountziaris, AG Mikos - Tissue Engineering Part B: Reviews, 2008 - liebertpub.com
Proinflammatory cytokines are infamous for their catabolic effects on tissues and joints in
both inflammatory diseases and following the implantation of biomedical devices. However …

Retrospective cohort study of 4,591 dental implants: Analysis of risk indicators for bone loss and prevalence of peri‐implant mucositis and peri‐implantitis

D French, HM Grandin, R Ofec - Journal of Periodontology, 2019 - Wiley Online Library
Background Due to the risk of peri‐implantitis, following dental implant placement, this study
aimed to evaluate risk indicators associated with marginal bone loss from a retrospective …

Fracture healing physiology and the quest for therapies for delayed healing and nonunion

P Kostenuik, FM Mirza - Journal of Orthopaedic Research®, 2017 - Wiley Online Library
Delayed healing and nonunion of fractures represent enormous burdens to patients and
healthcare systems. There are currently no approved pharmacological agents for the …

Inhibition of fracture healing

MS Gaston, A Simpson - The Journal of Bone & Joint Surgery …, 2007 - boneandjoint.org.uk
Inhibition of fracture healing | Bone & Joint header advert Bone and Joint logo Journals &
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CD169+ macrophages are critical for osteoblast maintenance and promote intramembranous and endochondral ossification during bone repair

L Batoon, SM Millard, ME Wullschleger, C Preda… - Biomaterials, 2019 - Elsevier
Osteal macrophages (osteomacs) contribute to bone homeostasis and regeneration. To
further distinguish their functions from osteoclasts, which share many markers and growth …

Mechanics and mechano-biology of fracture healing in normal and osteoporotic bone

P Augat, U Simon, A Liedert, L Claes - Osteoporosis international, 2005 - Springer
Fracture repair, which aims at regaining the functional competence of a bone, is a complex
and multifactorial process. For the success of fracture repair biology and mechanics are of …

Harnessing and modulating inflammation in strategies for bone regeneration

PM Mountziaris, PP Spicer, FK Kasper… - … Engineering Part B …, 2011 - liebertpub.com
Inflammation is an immediate response that plays a critical role in healing after fracture or
injury to bone. However, in certain clinical contexts, such as in inflammatory diseases or in …

In vivo models of bone repair

LA Mills, A Simpson - The Journal of Bone & Joint Surgery …, 2012 - boneandjoint.org.uk
This review is aimed at clinicians appraising preclinical trauma studies and researchers
investigating compromised bone healing or novel treatments for fractures. It categorises the …

Effects of perioperative antiinflammatory and immunomodulating therapy on surgical wound healing

AJ Busti, JS Hooper, CJ Amaya… - … : The Journal of Human …, 2005 - Wiley Online Library
Patients with various rheumatologic and inflammatory disease states commonly require
drugs known to decrease the inflammatory or autoimmune response for adequate control of …