Obesity paradox in cardiovascular disease: where do we stand?
Obesity is associated with an increased risk of developing cardiovascular disease (CVD),
particularly heart failure (HF) and coronary heart disease (CHD). The mechanisms through …
particularly heart failure (HF) and coronary heart disease (CHD). The mechanisms through …
Obesity, risk of diabetes and role of physical activity, exercise training and cardiorespiratory fitness
The epidemic of obesity contributes to the burden of type 2 diabetes mellitus (T2DM) in the
United States and worldwide. Importantly, obesity is not only preventable but can be treated …
United States and worldwide. Importantly, obesity is not only preventable but can be treated …
Heart failure with preserved ejection fraction in humans and mice: embracing clinical complexity in mouse models
Heart failure (HF) with preserved ejection fraction (HFpEF) is a multifactorial disease
accounting for a large and increasing proportion of all clinical HF presentations. As a clinical …
accounting for a large and increasing proportion of all clinical HF presentations. As a clinical …
Mechanisms underlying direct actions of hyperlipidemia on myocardium: an updated review
YS Yao, TD Li, ZH Zeng - Lipids in Health and Disease, 2020 - Springer
Hyperlipidemia is a common metabolic disorder and one of risk factors for cardiovascular
disease. Clinical studies have shown that hyperlipidemia increases the risk of non-ischemic …
disease. Clinical studies have shown that hyperlipidemia increases the risk of non-ischemic …
An overview of murine high fat diet as a model for type 2 diabetes mellitus
A Heydemann - Journal of diabetes research, 2016 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) is a worldwide epidemic, which by all predictions will only
increase. To help in combating the devastating array of phenotypes associated with T2DM a …
increase. To help in combating the devastating array of phenotypes associated with T2DM a …
Gut microbiota-dependent metabolite trimethylamine N-oxide contributes to cardiac dysfunction in western diet-induced obese mice
K Chen, X Zheng, M Feng, D Li, H Zhang - Frontiers in physiology, 2017 - frontiersin.org
Excessive consumption of diets high in sugars and saturated fat, frequently known as
western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows …
western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows …
Obesity and heart failure: focus on the obesity paradox
The escalating prevalence of obesity has been linked to substantial increases in both
metabolic and cardiovascular disease. Nevertheless, the direct effects of obesity on …
metabolic and cardiovascular disease. Nevertheless, the direct effects of obesity on …
The role of diet and nutrition in heart failure: A state-of-the-art narrative review
Heart Failure (HF) incidence is increasing steadily worldwide, while prognosis remains poor.
Though nutrition is a lifestyle factor implicated in prevention of HF, little is known about the …
Though nutrition is a lifestyle factor implicated in prevention of HF, little is known about the …
Characterization of inflammation and insulin resistance in high‐fat diet‐induced male C57BL/6J mouse model of obesity
Background Animal models of diet‐induced obesity (DIO) are commonly used in medical
research for mimicking human diseases. There is no universal animal model, and careful …
research for mimicking human diseases. There is no universal animal model, and careful …
Dietary fat, sugar consumption, and cardiorespiratory fitness in patients with heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) is associated with obesity and,
indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely …
indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely …