[HTML][HTML] Glucosinolate structural diversity, identification, chemical synthesis and metabolism in plants

I Blažević, S Montaut, F Burčul, CE Olsen, M Burow… - Phytochemistry, 2020 - Elsevier
The glucosinolates (GSLs) is a well-defined group of plant metabolites characterized by
having an S-β-d-glucopyrano unit anomerically connected to an O-sulfated (Z) …

Fruit and vegetable consumption and health outcomes: an umbrella review of observational studies

D Angelino, J Godos, F Ghelfi, M Tieri… - … journal of food …, 2019 - Taylor & Francis
The aim of this study was to provide a comprehensive evaluation of current evidence on fruit
and vegetable consumption and health outcomes. A systematic search for quantitative …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

Retrograde sulfur flow from glucosinolates to cysteine in Arabidopsis thaliana

R Sugiyama, R Li, A Kuwahara… - Proceedings of the …, 2021 - National Acad Sciences
Specialized (secondary) metabolic pathways in plants have long been considered one-way
routes of leading primary metabolite precursors to bioactive end products. Conversely …

Glucosinolates: Molecular structure, breakdown, genetic, bioavailability, properties and healthy and adverse effects

MA Prieto, CJ López, J Simal-Gandara - Advances in food and Nutrition …, 2019 - Elsevier
Glucosinolates are a large group of plant secondary metabolites with nutritional effects and
biologically active compounds. Glucosinolates are mainly found in cruciferous plants such …

Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment

M Russo, C Spagnuolo, GL Russo… - Critical reviews in …, 2018 - Taylor & Francis
In the past decades, extensive studies have reported the potential chemopreventive activity
of sulforaphane, an isothiocyanate derived from glucoraphanin, occurring in large amounts …

Concentrations of thiocyanate and goitrin in human plasma, their precursor concentrations in brassica vegetables, and associated potential risk for hypothyroidism

P Felker, R Bunch, AM Leung - Nutrition reviews, 2016 - academic.oup.com
Brassica vegetables are common components of the diet and have beneficial as well as
potentially adverse health effects. Following enzymatic breakdown, some glucosinolates in …

Sulforaphane-role in aging and neurodegeneration

R Santín-Márquez, A Alarcón-Aguilar… - Geroscience, 2019 - Springer
In the last several years, numerous molecules derived from plants and vegetables have
been tested for their antioxidant, anti-inflammatory, and anti-aging properties. One of them is …

The role of isothiocyanates as cancer chemo-preventive, chemo-therapeutic and anti-melanoma agents

M Mitsiogianni, G Koutsidis, N Mavroudis, DT Trafalis… - Antioxidants, 2019 - mdpi.com
Many studies have shown evidence in support of the beneficial effects of phytochemicals in
preventing chronic diseases, including cancer. Among such phytochemicals, sulphur …

Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects

MT López-Chillón, C Carazo-Díaz, D Prieto-Merino… - Clinical Nutrition, 2019 - Elsevier
Background & aims Broccoli sprouts represent an interesting choice of healthy food product
as they are rich in glucosinolates and their cognate bioactive metabolites, isothiocyanates …