Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

MicroRNAs (miRNAs) are a group of small non-coding RNAs present in a wide diversity of
organisms. MiRNAs regulate gene expression at a post-transcriptional level through their …

Emerging diseases have significantly impacted the last few decades (1–10). The emergence
and re-emergence of vector-borne and zoonotic diseases in Africa, Asia, and Latin America …

Toxoplasma gondii is an intracellular parasite with a worldwide distribution. Toxoplasma
gondii infections are of great concern for public health, and their impact is usually most …

Background Recently, immunotherapy has become very hopeful for cancer therapy. Cancer
treatment through immunotherapy has excellent specificity and less toxicity than …

cGAS-STING signaling is a major pathway in inducing type Ⅰ IFN, which plays a crucial role
in the defense against T. gondii infection. In contrast, T. gondii develops multiple strategies …

Background: There is currently no clear evidence of the effectiveness of antibiotic therapy in
acute ocular toxoplasmosis (OT), but its effect as a secondary prophylaxis is undisputed. The …

Dendritic cells and macrophages are integral parts of the innate immune system and
gatekeepers against infection. The protozoan pathogen, Toxoplasma gondii, is known to …

Background Colombia implemented the world's first evidence-based guidelines for
congenital toxoplasmosis in 2013, no evaluation of its impact has been reported. Methods …

Ocular toxoplasmosis (OT) is characterized by inflammation within the eye and is the most
recognized clinical manifestation of toxoplasmosis. The objective of this study was to identify …