Toxic optic neuropathy (TON) is caused by the damage to the optic nerve through different
toxins, including drugs, metals, organic solvents, methanol and carbon dioxide. A similar …

Adverse drug reaction is defined by the World Health Organization as any response to a
drug that is noxious and unintended and occurs at a dose normally used in man. Older …

Drugs across many pharmacologic classes induce corneal epithelial changes. Many of
these drugs have cationic amphiphilic structures, with a hydrophobic ring and hydrophilic …

Although amiodarone is the most commonly prescribed anti-arrhythmic drug, its use is
limited by serious toxicities, including optic neuropathy. Current reports of amiodarone …

Impairments of sensory perception that occur during a period of critical care can seriously
impact on health and nutritional status, activities of daily living, independence, quality of life …

Amiodarone, a bi-iodinated benzofuran derivative, is among the most commonly used
antiarrhythmic drugs due to its high level of effectiveness. Though initially categorized as a …

The pharmacological management of atrial fibrillation (AF) requires careful consideration
from a safety perspective. This article focuses primarily on maintenance therapy using …

Amiodarone-associated optic neuropathy (AAON) is a complex clinical diagnosis, requiring
distinction from non-arteritic ischemic optic neuropathy (NAION) due to a shared at-risk …

Background Ocular toxicity is a severe adverse effect that limits the chronic clinical use of the
antiarrhythmic drug amiodarone. Here, we aimed to evaluate the cytoprotective effect of …

Purpose To investigate whether amiodarone use is associated with an increased risk of
optic neuropathy. Design Retrospective population-based cohort study. Participants Patients …