The role of exosome and the ESCRT pathway on enveloped virus infection

Y Ju, H Bai, L Ren, L Zhang - International Journal of Molecular Sciences, 2021 - mdpi.com
The endosomal sorting complex required for transport (ESCRT) system consists of
peripheral membrane protein complexes ESCRT-0,-I,-II,-III VPS4-VTA1, and ALIX …

Release of HSV-1 cell-free Virions: mechanisms, regulation, and likely role in human-human transmission

SA Rice - Viruses, 2021 - mdpi.com
Herpes simplex virus type 1, or HSV-1, is a widespread human pathogen that replicates in
epithelial cells of the body surface and then establishes latent infection in peripheral …

ESCRT machinery and virus infection

J Dai, Y Feng, Y Liao, L Tan, Y Sun, C Song, X Qiu… - Antiviral Research, 2024 - Elsevier
The endosomal sorting complex required for transport (ESCRT) machinery plays a
significant role in the spread of human viruses. However, our understanding of how the host …

[HTML][HTML] Live-cell fluorescence microscopy of HSV-1 cellular egress by exocytosis

MH Bergeman, MQ Hernandez, J Diefenderfer… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Abstract The human pathogen Herpes Simplex Virus 1 (HSV-1) produces a lifelong infection
in the majority of the world's population. While the generalities of alpha herpesvirus …

Mutation of phenylalanine 23 of Newcastle disease virus matrix protein inhibits virus release by disrupting the interaction between the FPIV L-domain and charged …

Y Pei, J Xue, Q Teng, D Feng, M Huang… - Microbiology …, 2023 - Am Soc Microbiol
The matrix (M) protein FPIV L-domain is conserved among multiple paramyxoviruses;
however, its function and the associated mechanism remain unclear. In this study, the …

LINC08148 promotes the caveola-mediated endocytosis of Zika virus through upregulating transcription of Src

Z Huo, X Zhu, Q Peng, C Chen, X Yang… - Journal of …, 2024 - Am Soc Microbiol
Long non-coding RNAs (lncRNAs) represent a new group of host factors involved in viral
infection. Current study identified an intergenic lncRNA, LINC08148, as a proviral factor of …

Individual herpes simplex virus 1 (HSV-1) particles exit by exocytosis and accumulate at preferential egress sites

MH Bergeman, MQ Hernandez, J Diefenderfer… - Journal of …, 2024 - Am Soc Microbiol
The human pathogen herpes simplex virus 1 (HSV-1) produces a lifelong infection in the
majority of the world's population. While the generalities of alpha herpesvirus assembly and …

Research progress on the mechanism of exosome-mediated virus infection

H Zhang, X Liu, J Shi, X Su, J Xie, Q Meng… - Frontiers in Cellular …, 2024 - frontiersin.org
Exosomes are extracelluar vesicles that facilitate intercellular communication and are pivotal
in post-transcriptional regulation within cellular gene regulatory networks, impacting …

Cytomegaloviruses reorganize endomembrane system to intersect endosomal and amphisome-like egress pathway

P Lučin, H Mahmutefendić Lučin… - Frontiers in cell and …, 2023 - frontiersin.org
Cytomegaloviruses (CMV) cause productive, persistent or latent infections in their hosts.
Productive infection requires the establishment of a complete manufacturing chain in the …

Virus–Host Protein Interaction Network of the Hepatitis E Virus ORF2-4 by Mammalian Two-Hybrid Assays

L Corneillie, I Lemmens, K Weening, A De Meyer… - Viruses, 2023 - mdpi.com
Throughout their life cycle, viruses interact with cellular host factors, thereby influencing
propagation, host range, cell tropism and pathogenesis. The hepatitis E virus (HEV) is an …