Lysophosphatidic acid (LPA) refers to a family of simple phospholipids that act as ligands for
G protein-coupled receptors. While LPA exerts effects throughout the body in normal …

Lysophosphatidic acid (LPA) is a collective name for a set of bioactive lipid species. Via six
widely distributed G protein-coupled receptors (GPCRs), LPA elicits a plethora of biological …

The lipid mediator lysophosphatidic acid (LPA) plays a role in cancer progression and
signals via specific G protein–coupled receptors, LPA1-3. LPA has been shown to enhance …

Apicomplexan parasites invade host cells in an active process involving their ability to move
by gliding motility. While the acto-myosin system of the parasite plays a crucial role in the …

Although noroviruses cause the vast majority of nonbacterial gastroenteritis in humans, little
is known about their life cycle, including viral entry. Murine norovirus (MNV) is the only …

Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus and one of the most
common agents of viral encephalitis. The infectious entry process of JEV into host cells …

Endocytosis is a key regulatory mechanism adopted by G protein-coupled receptors
(GPCRs) to modulate downstream signaling responses within a stringent spatiotemporal …

Endocytosis and intracellular trafficking constitute important regulatory features associated
with G protein-coupled receptor (GPCR) function. GPCR endocytosis involves several …

Myocardin-related transcription factors A and B (MRTFs) are coactivators of Serum
Response Factor (SRF), which controls fundamental biological processes such as cell …

β-arrestins play critical roles in chemotaxis and cytoskeletal reorganization downstream of
several receptor types, including G protein-coupled receptors (GPCRs), which are targets for …