Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events

M Conti, F Franciosi - Human reproduction update, 2018 - academic.oup.com
Infertility affects~ 7% of couples of reproductive age with little change in incidence in the last
two decades. ART, as well as other interventions, have made major strides in correcting this …

Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings

P Guerin, S El Mouatassim… - Human reproduction …, 2001 - academic.oup.com
Oxidative stress is involved in the aetiology of defective embryo development. Reactive
oxygen species (ROS) may originate from embryo metabolism and/or embryo surroundings …

Alterations of expression of developmentally important genes in preimplantation bovine embryos by in vitro culture conditions: implications for subsequent …

H Niemann, C Wrenzycki - Theriogenology, 2000 - Elsevier
Recent advances in molecular technology and in vitro production of bovine embryos have
enabled studies of gene transcription in preimplantation embryos. On the basis of …

Oocyte cytoplasmic maturation: a key mediator of oocyte and embryo developmental competence

AJ Watson - Journal of animal science, 2007 - academic.oup.com
Efforts have intensified to successfully mature and inseminate oocytes in vitro and then
culture ensuing embryos to transferable stages from a large number of mammalian species …

Expression of genes encoding antioxidant enzymes in human and mouse oocytes during the final stages of maturation

S El Mouatassim, P Guerin… - Molecular human …, 1999 - academic.oup.com
The mRNA expression of five enzymes: catalase, Cu-Zn-superoxide dismutase (Cu-Zn-
SOD), Mn-superoxide dismutase (Mn-SOD), glutathione peroxidase (GPX), and γ …

The maternal legacy to the embryo: cytoplasmic components and their effects on early development

TALB Gandolfi, F Gandolfi - Theriogenology, 2001 - Elsevier
RNA molecules and proteins are accumulated in the oocyte cytoplasm during its growth
phase and are used to sustain the early phases of embryonic development before embryo …

Effect of heat stress on reproduction in dairy cows: insights into the cellular and molecular responses of the oocyte

Z Roth - Annual review of animal biosciences, 2017 - annualreviews.org
Among the components of the female reproductive tract, the ovarian pool of follicles and
their enclosed oocytes are highly sensitive to hyperthermia. Heat-induced alterations in …

Molecular control of mitochondrial function in preimplantation mouse embryos

J Thundathil, F Filion, LC Smith - Molecular reproduction and …, 2005 - Wiley Online Library
Mitochondria play a key role in a number of physiological events during all stages of life,
including the very first stages following fertilization. It is, therefore, important to understand …

Impact of bovine oocyte maturation media on oocyte transcript levels, blastocyst development, cell number, and apoptosis

AJ Watson, P De Sousa, A Caveney… - Biology of …, 2000 - academic.oup.com
The objectives were 1) to investigate the effects of oocyte maturation in serum-free and
amino acid-supplemented defined media on oocyte transcript levels, blastocyst cell number …

Towards a better understanding of RNA carriage by ejaculate spermatozoa

D Miller, GC Ostermeier - Human reproduction update, 2006 - academic.oup.com
Research on spermatozoal RNA has made considerable progress since the original reports
on its presence appeared in the late 1950s and early 1960s. Through the use of stringent …