International consensus diagnostic criteria for neuromyelitis optica spectrum disorders

DM Wingerchuk, B Banwell, JL Bennett, P Cabre… - Neurology, 2015 - AAN Enterprises
Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple
sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G antibodies …

Hope for patients with neuromyelitis optica spectrum disorders—from mechanisms to trials

SJ Pittock, A Zekeridou, BG Weinshenker - Nature Reviews Neurology, 2021 - nature.com
Neuromyelitis optica spectrum disorder (NMOSD) is a rare inflammatory CNS disease that
primarily manifests as relapsing episodes of severe optic neuritis and myelitis. Diagnosis of …

Myelin oligodendrocyte glycoprotein antibody–positive optic neuritis: clinical characteristics, radiologic clues, and outcome

JJ Chen, EP Flanagan, J Jitprapaikulsan… - American journal of …, 2018 - Elsevier
Purpose To characterize the clinical phenotype of myelin oligodendrocyte glycoprotein
antibody (MOG-IgG) optic neuritis. Design Observational case series. Methods Setting …

MRI characteristics of neuromyelitis optica spectrum disorder: an international update

HJ Kim, F Paul, MA Lana-Peixoto, S Tenembaum… - Neurology, 2015 - AAN Enterprises
Since its initial reports in the 19th century, neuromyelitis optica (NMO) had been thought to
involve only the optic nerves and spinal cord. However, the discovery of highly specific anti …

Optic neuritis

AT Toosy, DF Mason, DH Miller - The Lancet Neurology, 2014 - thelancet.com
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)

C Trebst, S Jarius, A Berthele, F Paul, S Schippling… - Journal of …, 2014 - Springer
Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

New therapies for neuromyelitis optica spectrum disorder

M Levy, K Fujihara, J Palace - The Lancet Neurology, 2021 - thelancet.com
Background Neuromyelitis optica spectrum disorder is an autoimmune disease of the CNS
that primarily affects the optic nerves and spinal cord. Most patients have serum antibodies …

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: a multicentre study of 175 patients

S Jarius, K Ruprecht, B Wildemann, T Kuempfel… - Journal of …, 2012 - Springer
Background The diagnostic and pathophysiological relevance of antibodies to aquaporin-4
(AQP4-Ab) in patients with neuromyelitis optica spectrum disorders (NMOSD) has been …

MOG antibody disease: a review of MOG antibody seropositive neuromyelitis optica spectrum disorder

R Narayan, A Simpson, K Fritsche, S Salama… - Multiple sclerosis and …, 2018 - Elsevier
MOG antibody disease is an autoimmune disease of the central nervous system associated
with a serological antibody against MOG, myelin oligodendrocyte glycoprotein. MOG is a …

Efficacy and safety of rituximab therapy in neuromyelitis optica spectrum disorders: a systematic review and meta-analysis

V Damato, A Evoli, R Iorio - JAMA neurology, 2016 - jamanetwork.com
Importance Neuromyelitis optica spectrum disorders (NMOSDs) are autoimmune
astrocytopathies characterized by predominant involvement of the optic nerves and spinal …