Pirfenidone: a promising drug in ocular therapeutics
Pirfenidone, initially indicated for lung fibrosis, has gone beyond its original purpose, and
shown promise in eye care. This detailed review tracks its evolution from lung treatment to …
shown promise in eye care. This detailed review tracks its evolution from lung treatment to …
Therapeutic candidates for keloid scars identified by qualitative review of scratch assay research for wound healing
ME Alishahedani, M Yadav, KJ McCann, P Gough… - PLoS …, 2021 - journals.plos.org
The scratch assay is an in vitro technique used to analyze cell migration, proliferation, and
cell-to-cell interaction. In the assay, cells are grown to confluence and then 'scratched'with a …
cell-to-cell interaction. In the assay, cells are grown to confluence and then 'scratched'with a …
[HTML][HTML] Pirfenidone inhibits stromal collagen deposition and improves intra-tumoral delivery and antitumor efficacy of Pegylated liposomal doxorubicin
T Cai, J Jiang, W Yao, Y Hu, S Kong, Q Fan… - Biomedicine & …, 2023 - Elsevier
The effectiveness of cancer nanotherapeutics is greatly restricted by the dense collagen
network in solid tumors. Pirfenidone (PFD) is a clinically approved oral antifibrotic agent …
network in solid tumors. Pirfenidone (PFD) is a clinically approved oral antifibrotic agent …
Pirfenidone attenuates synovial fibrosis and postpones the progression of osteoarthritis by anti-fibrotic and anti-inflammatory properties in vivo and in vitro
Q Wei, N Kong, X Liu, R Tian, M Jiao, Y Li… - Journal of Translational …, 2021 - Springer
Background Osteoarthritis (OA) is a disease of the entire joint involving synovial fibrosis and
inflammation. Pathological changes to the synovium can accelerate the progression of OA …
inflammation. Pathological changes to the synovium can accelerate the progression of OA …
Effect of Pirfenidone on TGF-β1-induced myofibroblast differentiation and extracellular matrix homeostasis of human orbital fibroblasts in graves' ophthalmopathy
Pirfenidone is a pyridinone derivative that has been shown to inhibit fibrosis in animal
models and in patients with idiopathic pulmonary fibrosis. Its effect on orbital fibroblasts …
models and in patients with idiopathic pulmonary fibrosis. Its effect on orbital fibroblasts …
Pirfenidone Attenuates the EMT Process and the Secretion of VEGF in TGF‐β2‐Induced ARPE‐19 Cells via Inhibiting the Activation of the NF‐κB/Snail Signaling …
H Li, L Wang, M Shao, M Ren, W Zhang… - Journal of …, 2023 - Wiley Online Library
Aim. Pirfenidone (PFD), an antifibrotic drug, has various beneficial functions such as
antioxidant, antifibrotic, and anti‐inflammatory effects. This study aimed to explore the …
antioxidant, antifibrotic, and anti‐inflammatory effects. This study aimed to explore the …
Mitomycin C, curcumin, and fibrin glue inhibit the cell proliferation and expression of TGF-β in human pterygium fibroblast
M Abdurrauf, F Ramadhan, I Zuhria… - Bali Medical …, 2022 - repository.unair.ac.id
3. Tidak masuk pada predatory baik jurnal, publisher, dan hijacked 4. Syarat komposisi
Editor Board: Terdiri lebih dari 4 negara 5. Syarat kontributor penulis artikel: Penulis ke 6 …
Editor Board: Terdiri lebih dari 4 negara 5. Syarat kontributor penulis artikel: Penulis ke 6 …
PKM2/Hif-1α signal suppression involved in therapeutics of pulmonary fibrosis with microcystin-RR but not with pirfenidone
Y Ren, J Wang, W Guo, J Chen, L Xu, Z Wu, Y Wang - Toxicon, 2024 - Elsevier
To date there are only pirfenidone (PFD) and nintedanib to be given conditional
recommendation in idiopathic pulmonary fibrosis (IPF) therapies with slowing disease …
recommendation in idiopathic pulmonary fibrosis (IPF) therapies with slowing disease …
Risk factors for pterygium: latest research progress on major pathogenesis
P Ding, Y Zhang, Y He - Experimental Eye Research, 2024 - Elsevier
A pterygium is a wedge-shaped fibrovascular growth of the conjunctiva membrane that
extends onto the cornea, which is the outer layer of the eye. It is also known as surfer's eye …
extends onto the cornea, which is the outer layer of the eye. It is also known as surfer's eye …
Prognostic impact of cytokines and chemokines in bronchoalveolar lavage fluid on acute exacerbation of fibrosing interstitial lung disease
K Furuta, D Fujimoto, A Matsunashi, R Shibaki… - Respiratory …, 2024 - Elsevier
Background and objective Acute exacerbation of fibrosing interstitial lung disease (AE-FILD)
is a serious condition with a high mortality rate. We aimed to comprehensively analyze …
is a serious condition with a high mortality rate. We aimed to comprehensively analyze …