Bioengineering of microalgae: recent advances, perspectives, and regulatory challenges for industrial application

G Kumar, A Shekh, S Jakhu, Y Sharma… - … in Bioengineering and …, 2020 - frontiersin.org
Microalgae, due to their complex metabolic capacity, are being continuously explored for
nutraceuticals, pharmaceuticals, and other industrially important bioactives. However …

A series of fortunate events: introducing Chlamydomonas as a reference organism

PA Salomé, SS Merchant - The Plant Cell, 2019 - academic.oup.com
The unicellular alga Chlamydomonas reinhardtii is a classical reference organism for
studying photosynthesis, chloroplast biology, cell cycle control, and cilia structure and …

A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis

X Li, W Patena, F Fauser, RE Jinkerson, S Saroussi… - Nature …, 2019 - nature.com
Photosynthetic organisms provide food and energy for nearly all life on Earth, yet half of their
protein-coding genes remain uncharacterized,. Characterization of these genes could be …

An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii

X Li, R Zhang, W Patena, SS Gang, SR Blum… - The Plant …, 2016 - academic.oup.com
The green alga Chlamydomonas reinhardtii is a leading unicellular model for dissecting
biological processes in photosynthetic eukaryotes. However, its usefulness has been limited …

The CO2 concentrating mechanism and photosynthetic carbon assimilation in limiting CO2: how Chlamydomonas works against the gradient

Y Wang, DJ Stessman, MH Spalding - The Plant Journal, 2015 - Wiley Online Library
The CO 2 concentrating mechanism (CCM) represents an effective strategy for carbon
acquisition that enables microalgae to survive and proliferate when the CO 2 concentration …

NTRC regulates CP12 to activate Calvin–Benson cycle during cold acclimation

JT Teh, V Leitz, VJC Holzer… - Proceedings of the …, 2023 - National Acad Sciences
NADPH-dependent thioredoxin reductase C (NTRC) is a chloroplast redox regulator in
algae and plants. Here, we used site-specific mutation analyses of the thioredoxin domain …

Systematic identification and characterization of genes in the regulation and biogenesis of photosynthetic machinery

M Kafri, W Patena, L Martin, L Wang, G Gomer… - Cell, 2023 - cell.com
Photosynthesis is central to food production and the Earth's biogeochemistry, yet the
molecular basis for its regulation remains poorly understood. Here, using high-throughput …

Comparative and functional algal genomics

CE Blaby-Haas, SS Merchant - Annual Review of Plant Biology, 2019 - annualreviews.org
Over 100 whole-genome sequences from algae are published or soon to be published. The
rapidly increasing availability of these fundamental resources is changing how we …

CaM and CML emergence in the green lineage

X Zhu, C Dunand, W Snedden, JP Galaud - Trends in Plant Science, 2015 - cell.com
Calmodulin (CaM) is a well-studied calcium sensor that is ubiquitous in all eukaryotes and
contributes to signaling during developmental processes and adaptation to environmental …

Harnessing the power of mutagenesis and adaptive laboratory evolution for high lipid production by oleaginous microalgae and yeasts

N Arora, HW Yen, GP Philippidis - Sustainability, 2020 - mdpi.com
Oleaginous microalgae and yeasts represent promising candidates for large-scale
production of lipids, which can be utilized for production of drop-in biofuels, nutraceuticals …