Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Chronic kidney disease (CKD) is a global health problem with rising incidence and
prevalence. Among several pathogenetic mechanisms responsible for disease progression …

Acute kidney injury (AKI) is a global public health concern associated with high morbidity
and mortality. Although advances in medical management have improved the in-hospital …

Acute kidney injury (AKI) and chronic kidney disease (CKD) are interconnected conditions,
and CKD is projected to become the fifth leading global cause of death by 2040. New …

Acute kidney injury (AKI) is a life-threatening condition that is one of most common side
effects of cisplatin therapy. Fatty acid oxidation (FAO) is the main source of energy …

Hypertension is one of the leading causes of chronic kidney disease characterized with
renal fibrosis. This study aimed to investigate roles and mechanisms of sirtuin 7 (SIRT7) in …

Background Acute kidney injury (AKI) is a common complication in clinical inpatients, and it
continues a high morbidity and mortality rate despite many clinical treatment measures. AKI …

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder with high
morbidity and mortality. The current study aims to explore the role of Cullin-associated and …

Lipotoxicity is the dysregulation of the lipid environment and/or intracellular composition that
leads to accumulation of harmful lipids and ultimately to organelle dysfunction, abnormal …

Numerous studies have proven the critical role of macrophages in the renal fibrosis process.
Notably, G Protein-coupled Estrogen Receptor 1 (GPER1), a novel estrogen receptor, has …